Name | PEPCK |
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Synonyms | Full length cDNA clone CS0DC022YA24 of Neuroblastoma of Homo sapiens; PEP carboxykinase; Phosphoenolpyruvate carboxylase; Mitochondrial phosphoenolpyruvate carboxykinase 2; PCK 2; PCK2; PCK2 protein; PEPCK… |
Name | sodium arsenite |
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CAS | sodium arsenenite |
PubMed | Abstract | RScore(About this table) | |
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18505831 | Chanda D, Kim SJ, Lee IK, Shong M, Choi HS: Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression. Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E368-79. Epub 2008 May 27. Sodium arsenite inhibited the promoter activity of PEPCK and G6Pase, and this repression was abolished by small interfering (si) RNA SHP treatments. |
169(2,2,3,4) | Details |
9712902 | Cheong J, Coligan JE, Shuman JD: Activating transcription factor-2 regulates phosphoenolpyruvate carboxykinase transcription through a stress-inducible mitogen-activated protein kinase pathway. J Biol Chem. 1998 Aug 28;273(35):22714-8. In this regard, we show that treatment with sodium arsenite, a known activator of p38 MAP kinases, also stimulates expression from the PEPCK promoter. |
81(1,1,1,1) | Details |
8971075 | Sutherland C, Tebbey PW, Granner DK: Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells. Diabetes. 1997 Jan;46(1):17-22. Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the rate-limiting step in hepatic gluconeogenesis. |
4(0,0,0,4) | Details |