Protein Information

Name mcl 1
Synonyms Bcl 2 related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl 1; MCL 1; MCL1; MCL1L; MCL1S; Myeloid cell leukemia 1…

Compound Information

Name 4-aminopyridine
CAS 4-pyridinamine

Reference List

PubMed Abstract RScore(About this table)
10556359 Wang L, Zhou P, Craig RW, Lu L: Protection from cell death by mcl-1 is mediated by membrane hyperpolarization induced by K (+) channel activation. J Membr Biol. 1999 Nov 15;172(2):113-20.

Suppression of K (+) channel activity by 4-aminopyridine (4-AP) before etoposide treatment significantly reduced the viability of mcl-1 transfected cells to 49.0 +/- 4.6%.
88(1,1,1,8) Details