| Name | eag |
|---|---|
| Synonyms | EAG; KV10.1; EAG 1; EAG1; Ether a go go potassium channel 1; KCNH 1; KCNH1; Potassium voltage gated channel subfamily H member 1… |
| Name | 4-aminopyridine |
|---|---|
| CAS | 4-pyridinamine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19332483 | Greenwood IA, Yeung SY, Tribe RM, Ohya S: Loss of functional K+ channels encoded by ether-a-go-go-related genes in mouse myometrium prior to labour onset. J Physiol. 2009 May 15;587(Pt 10):2313-26. Epub 2009 Mar 30. This study aimed to assess the expression of ERG1-3 (KCNH1-3) genes in the murine myometrium (smooth muscle layer of the uterus) and determine the functional impact of the ion channels encoded by these genes in pregnant and non-pregnant animals. |
1(0,0,0,1) | Details |
| 15749932 | Li GR, Sun H, Deng X, Lau CP: Characterization of ionic currents in human mesenchymal stem cells from bone marrow. Stem Cells. 2005 Mar;23(3):371-82. Three types of outward currents were found in hMSCs, including a noise-like rapidly activating outward current inhibited by the large conductance Ca (2+)-activated K (+) channel (I (KCa)) blocker iberiotoxin, a transient outward K (+) current (I (to)) suppressed by 4-aminopyridine (4-AP), and a delayed rectifier K (+) current (IK (DR))-like ether-a-go-go (eag) K (+) channel. |
31(0,1,1,1) | Details |
| 17687001 | Bai X, Ma J, Pan Z, Song YH, Freyberg S, Yan Y, Vykoukal D, Alt E: Electrophysiological properties of human adipose tissue-derived stem cells. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1539-50. Epub 2007 Aug 8. RT-PCR results confirmed the presence of ion channels at the mRNA level: Kv1.1, Kv2.1, Kv1.5, Kv7.3, Kv11.1, and hEAG1, possibly encoding I (KDR); MaxiK, KCNN3, and KCNN4 for I (KCa); Kv1.4, Kv4.1, Kv4.2, and Kv4.3 for I (to) and hNE-Na for I (Na.TTX). The I (KDR) was inhibited by tetraethyl ammonium (TEA) and 4-aminopyridine (4-AP), which significantly reduced the proliferation of hASCs in a dose-dependent manner (P < 0.05), as suggested by bromodeoxyurindine (BrdU) incorporation. |
1(0,0,0,1) | Details |