| Name | muscles |
|---|---|
| Synonyms | COX 7a M; COX VIIa M; COX7A; COX7A1; COX7A1 protein; COX7AH; COX7AM; Cytochrome c oxidase subunit 7a H… |
| Name | 2,4-D |
|---|---|
| CAS | 2-(2,4-dichlorophenoxy)acetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 492213 | Eberstein A, Goodgold J: Experimental myotonia induced in denervated muscles by 2,4-D. . Muscle Nerve. 1979 Sep-Oct;2(5):364-8. |
12(0,0,2,2) | Details |
| 232748 | Muhlrad A, Friedman M: Myosin changes in experimental 2,4-dichlorophenoxyacetate myopathy. . Muscle Nerve. 1978 Nov-Dec;1(6):471-8. Young rats treated with 10 to 14 daily injections of 2,4-dichlorophenoxyacetate (2,4-D) developed a myopathy mainly involving fast muscles. |
7(0,0,1,2) | Details |
| 3972054 | Bernard PA, Toyoshima E, Eccles CU, Mayer RF, Johnson KP, Max SR: 2,4-Dichlorophenoxyacetic acid (2,4-D) reduces acetylcholinesterase activity in rat muscle. Exp Neurol. 1985 Mar;87(3):544-56. A single dose (200 mg/kg body weight, i.p.) of 2,4-dichlorophenoxyacetic acid (2,4-D), commonly used as a herbicide, caused significant decreases in acetylcholinesterase (AChE) activity in diaphragm and other muscles of the rat. |
6(0,0,1,1) | Details |
| 2268365 | Duffard RO, Arguello JM, Evangelista de Duffard AM: Biochemical alterations in skeletal muscle induced by 2,4-dichlorophenoxyacetic butyl ester during chick embryonic development. Biochem Pharmacol. 1990 Dec 1;40(11):2433-40. 2,4-Dichlorophenoxyacetic butyl ester (2,4-D b.e.) (3.1 mg/egg) was applied on fertile hen eggs before starting the incubation. Chicks hatched from treated eggs showed motor dysfunctions, postural troubles and edematous muscles. |
5(0,0,0,5) | Details |
| 9478089 | Kossmann S, Konieczny B, Hoffmann A: The role of respiratory muscles in the impairment of the respiratory system function in the workers of a chemical plant division producing pesticides. Przegl Lek. 1997;54(10):702-6. Workers of a chemical plant department producing dust and liquid pesticides (37 males and 17 females) exposed to dust containing free organic solvents and active substances, among others: organophosphate compounds, pyrethroids, triazines, carbamates and dithiocarbamates, 2,4-D, captan, carboxine, carbendazim and dodine were studied. |
3(0,0,0,3) | Details |
| 20045836 | Chen AV, Bagley RS, Talcott PA: Confirmed 2,4-dichlorophenoxyacetic acid toxicosis in a dog. J Am Anim Hosp Assoc. 2010 Jan-Feb;46(1):43-7. Percussion of the proximal appendicular muscles with a reflex hammer resulted in formation of dimples consistent with myotonia. Residues of 2,4-dichlorophenoxyacetic acid (2,4-D) were detected in both serum and urine. |
1(0,0,0,1) | Details |
| 750919 | Danon JM, Karpati G, Carpenter S: Subacute skeletal myopathy induced by 2,4-dichlorophenoxyacetate in rats and guinea pigs. Muscle Nerve. 1978 Mar-Apr;1(2):89-102. Rats and guinea pigs were injected with 2,4-dichlorophenoxyacetate (2,4-D) in amounts sufficient to keep them myotonic for over 12 hr daily. The biceps brachii muscles were studied by histochemistry, epoxy resin histology, and electron microscopy after one to five days. |
1(0,0,0,1) | Details |
| 977082 | Amma RM, Francis CM: Effect of 2,4-dichlorophenoxy on rabbit duodenum. . Indian J Physiol Pharmacol. 1976 Jul-Sep;20(3):153-5. 2,4-dichlorophenoxy (2,4-D) produces myotonia in healthy animals. The action of this drug was studied on smooth muscles in vitro using isolated strips of rabbit's duodenum. |
1(0,0,0,1) | Details |
| 6773743 | Zett L, Wagner A: Myotonic effects of 2,4-Dichlorphenoxyacetate (2,4-D) on the isolated frog skeletal muscle (author's transl)]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1980 Mar;11(1):6-11. |
0(0,0,0,0) | Details |
| 3585404 | Steiss JE, Braund KG, Clark EG: Neuromuscular effects of acute 2,4-dichlorophenoxyacetic acid (2,4-D) exposure in dogs. J Neurol Sci. 1987 May;78(3):295-301. Samples of the medial and lateral plantar nerves were removed for teased fiber and semi-thin section analysis; samples of appendicular muscles were removed for histology and histochemistry. |
1(0,0,0,1) | Details |
| 6603838 | Wagner A, Zett L: [Modification of 2,4-dichlorophenoxyacetate-induced myotonia of cold blood muscles by variations in external Ca++ and K+ concentrations]. Biomed Biochim Acta. 1983;42(1):95-108. The results show that 2,4-D blocks the Ca++-influx as well the transport of Na+ and K+ through the membrane. |
1(0,0,0,1) | Details |
| 2152293 | Ramirez BU: Energetic metabolism and fatigability in experimental myotonia. Arch Biol Med Exp. 1990 May;23(1):17-20. Experimental myotonia was induced in rats by 2,4-dichloro-phenoxyacetic acid (2,4-D). After 4 to 24 h of treatment, the anterior tibialis muscles exhibited increased fatigue at low frequency (30 Hz) nerve stimulation, but they developed normal tension at high-frequency (100 Hz) stimulation. |
1(0,0,0,1) | Details |
| 5839590 | Kuhn E, Stein W: [Model myotonia after 2,4-dichlorphenoxyacetate (2,4-D) in rats. Klin Wochenschr. 1965 Jun 15;43(12):673-7. In vitro and in vivo studies on the effects of 2,4-D on the energy metabolism of muscles] |
81(1,1,1,1) | Details |
| 3416978 | Ramirez BU, Soza MA: Intramuscular pH and endurance are abnormal in skeletal muscles from rats with experimental myotonia. Exp Neurol. 1988 Sep;101(3):347-55. The relation between resistance to fatigue and intramuscular pH was studied in fast muscles (anterior tibialis and extensor digitorum longus) from rats treated with 2,4-dichlorophenoxyacetic acid (2,4-D) to induce myotonia. |
21(0,0,3,6) | Details |
| 2148478 | Arguello JM, Evangelista de Duffard AM, Duffard RO: Ca2+ homeostasis alterations induced by 2,4-dichlorophenoxyacetic butyl ester and 2,4-dichlorophenoxyacetic acid on avian skeletal muscle. Biochem Pharmacol. 1990 Dec 1;40(11):2441-8. Isolated soleus muscles were treated with 2,4-dichlorophenoxyacetic acid (2,4-D) or 2,4-D b.e. [14C] 2,4-D reached it highest level in these muscles after 1 hr of treatment. |
13(0,0,2,3) | Details |