Protein Information

Name HGPRT
Synonyms HGPRT; hPrt1; HGPRTase; HPRT; HPRT 1; HPRT1 protein; Hypoxanthine phosphoribosyltransferase 1; Hypoxanthine guanine phosphoribosyltransferase…

Compound Information

Name 2,4-DB
CAS 4-(2,4-dichlorophenoxy)butanoic acid

Reference List

PubMed Abstract RScore(About this table)
11113700 Charles JM, Cifone MA, Lawlor T, Murli H, Young RR, Leeming NM: Evaluation of the in vitro genetic toxicity of 4-(2, 4-dichlorophenoxy) butyric acid. Mutat Res. 2000 Dec 20;472(1-2):75-83.

The genetic toxicity in vitro of the dimethylamine salt of 2,4-DB was examined by employing a range of end points including gene mutation in bacteria (Ames test) and mammalian cell cultures (CHO/HGPRT assay), cytogenetic abnormalities in mammalian cells (CHO/chromosomal aberration assay), and induction of DNA damage and repair in rat hepatocytes.
6(0,0,1,1) Details