Protein Information

Name von Willebrand factor
Synonyms Coagulation factor VIII VWF; F8VWF; VWD; VWF; Von Willebrand factor; von Willebrand factor precursor; Von Willebrand factors; von Willebrand factor precursors

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19234706 Sharma AK, Donovan JL, Hagerty JA, Sullivan RR, Edassery SL, Harrington DA, Cheng EY: Do current bladder smooth muscle cell isolation procedures result in a homogeneous cell population? Implications for bladder tissue engineering. World J Urol. 2009 Oct;27(5):687-94. Epub 2009 Feb 21.


Antibody staining of cultured cells consisted of alpha-SMA, von Willebrand factor, pan-cytokeratin, CD31, and CD90.
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18824769 Iwasaki K, Kojima K, Kodama S, Paz AC, Chambers M, Umezu M, Vacanti CA: Bioengineered three-layered robust and elastic artery using hemodynamically-equivalent pulsatile bioreactor. Circulation. 2008 Sep 30;118(14 Suppl):S52-7.


Scanning electron microscopic examination and Von Willebrand factor staining demonstrated the presence of ECs spread over the lumen.
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20051831 Kadono H, Furuzono T, Masuda M, Okada M, Ueki M, Takamizawa K, Tanaka R, Miyatake K, Koyama Y, Takakuda K: In vivo evaluation of hydroxyapatite nanocoating on polyester artificial vascular grafts and possibility as soft-tissue compatible material. ASAIO J. 2010 Jan-Feb;56(1):61-6.


A histologic evaluation was conducted by staining with hematoxylin and eosin (HE), the von Willebrand factor (vWf), and alpha-smooth muscle actin (alpha-SMA) around the inner lumen of the grafts.
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18177424 Ruger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hocker P, Dettke M: Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation. 2008 Sep;76(7):772-83. Epub 2008 Jan 3.


Developed vascular structures expressed the endothelial markers CD34, VEGFR-2, CD31, von Willebrand Factor (vWF), and podocalyxin, showed basement-membrane-lined lumina containing CD45+ cells and were surrounded by alpha-smooth muscle actin (SMA) expressing mural cells.
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18802012 Hao Q, Liu J, Pappu R, Su H, Rola R, Gabriel RA, Lee CZ, Young WL, Yang GY: Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2151-7. Epub 2008 Sep 18.


The GFP-positive BMDCs were colocalized with CD45 (94%), CD68 (71%), 5% Vimentin (5%), CD31/von Willebrand factor (vWF) (1%), and alpha-smooth muscle actin (alpha -SMA, 0.5%).
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18990339 Wang XB, Liu P, Tang ZP, Li FH, Liu CH, Hu YY, Xu LM: [Cordyceps mycelia extract decreases portal hypertension in rats with dimethylnitrosamine-induced liver cirrhosis: a study on its histological basis]. Zhong Xi Yi Jie He Xue Bao. 2008 Nov;6(11):1136-44.


The expressions of CD44, von Willebrand factor (vWF), laminin (LM), alpha-smooth muscle actin (alpha-SMA), type I collagen (Col I) and type IV collagen (Col IV) proteins in the hepatic sinusoida l walls were examined by immunohistochemistry.
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19679427 Bir SC, Esaki J, Marui A, Yamahara K, Tsubota H, Ikeda T, Sakata R: Angiogenic properties of sustained release platelet-rich plasma: characterization in-vitro and in the ischemic hind limb of the mouse. J Vasc Surg. 2009 Oct;50(4):870-879.e2. Epub 2009 Aug 12.


Endpoint evaluations were blood perfusion by laser Doppler perfusion image, vascular density by anti Von Willebrand factor (vWF), and mature vessel density by anti smooth muscle actin (SMA) antibody.
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19703598 Bloch K, Vanichkin A, Damshkaln LG, Lozinsky VI, Vardi P: Vascularization of wide pore agarose-gelatin cryogel scaffolds implanted subcutaneously in diabetic and non-diabetic mice. Acta Biomater. 2010 Mar;6(3):1200-5. Epub 2009 Aug 22.


The vascularization process was estimated using histological sections, in which endothelial cells were identified by Von Willebrand factor (vWF) and CD31 antigen staining and the pericyte layer was confirmed by alpha-smooth muscle actin (alpha-SMA) visualization.
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20010300 Yosef N, Xia RH, Ubogu EE: Development and characterization of a novel human in vitro blood-nerve barrier model using primary endoneurial endothelial cells. J Neuropathol Exp Neurol. 2010 Jan;69(1):82-97.


They rapidly differentiate to form capillary-like networks and microvessels, bind Ulex Europaeus Agglutinin 1 lectin, express von Willebrand factor, and endocytose acetylated low-density lipoprotein.
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20223267 Kelm JM, Lorber V, Snedeker JG, Schmidt D, Broggini-Tenzer A, Weisstanner M, Odermatt B, Mol A, Zund G, Hoerstrup SP: A novel concept for scaffold-free vessel tissue engineering: Self-assembly of microtissue building blocks. J Biotechnol. 2010 Mar 17.


The resulting vessels were analyzed by immunohistochemistry for extracellular matrix (ECM) and cell phenotype (von Willebrand factor, alpha-SMA, Ki67, VEGF).
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