SMA

Identification (Source:EPA,EU)

ID 954
Name SMA
CAS 3926-62-3
IUPAC sodium chloroacetate
Inchi InChI=1S/C2H3ClO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
CIPAC
EPA Code
Formula C2H2ClNaO2
SMILES ClC([H])([H])C(=O)[O-].[Na+]
Status Not Approved

Classification

Mode of Action
Pesticide Type
Chemical Group
Classification halogenated aliphatic herbicides

Properties (Source:PubChem)

Molecular Weight 116.47885
Physical State
AlogP -1.146
H-Bond Donor 0
H-Bond Acceptor 2
Surface Area 156.49
Polar Surface Area 100.95

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Related targets

Target Name RScore (About this table)
Smad (protein family or complex) 330(3,4,6,50) Details
transforming growth factor beta 1 341(2,4,4,121) Details
SMN1 740(2,3,6,535) Details
Nkx2.5 175(2,2,2,15) Details
smooth muscle actin 798(1,4,8,608) Details
Smad 3 173(1,3,5,23) Details
muscles 175(1,2,4,55) Details
snRNPs 146(1,2,2,36) Details
mitogen activated protein kinases (protein family or complex) 131(1,1,2,46) Details
p38 120(1,1,1,40) Details
beta actin 89(1,1,1,9) Details
myosin light chain kinase 87(1,1,1,7) Details
NMDA receptors (protein family or complex) 85(1,1,1,5) Details
P27 85(1,1,1,5) Details
KIP1 84(1,1,1,4) Details
CIP1 84(1,1,1,4) Details
fibroblast growth factor receptor 1 84(1,1,1,4) Details
beta globin 82(1,1,1,2) Details
calcineurin (protein family or complex) 81(1,1,1,1) Details
SMAD4 70(0,2,2,10) Details
S12 69(0,2,3,4) Details
fibronectin 147(0,1,1,117) Details
CD68 66(0,1,2,31) Details
ERK1 58(0,1,1,28) Details
TNFalpha 52(0,1,1,22) Details
myocardin 49(0,1,1,19) Details
protein C 46(0,1,2,11) Details
FSHbeta 42(0,1,2,7) Details
MMP1 39(0,1,1,9) Details
p65 38(0,1,2,3) Details
FRS2 35(0,1,1,5) Details
CK20 34(0,1,1,4) Details
CpG binding protein 34(0,1,1,4) Details
MBD2 34(0,1,1,4) Details
activins 34(0,1,1,4) Details
MBD1 33(0,1,1,3) Details
Smad 1 31(0,1,1,1) Details
methyl CpG binding domain protein 1 31(0,1,1,1) Details
Noggin 31(0,1,1,1) Details
Mad proteins 31(0,1,1,1) Details
methyl CpG binding domain protein 2 31(0,1,1,1) Details
sphingomyelinase 31(0,1,1,1) Details
activating transcription factor 2 31(0,1,1,1) Details
connective tissue growth factor 191(0,0,0,191) Details
vimentin 151(0,0,0,151) Details
E cadherin 142(0,0,0,142) Details
CD34 129(0,0,2,119) Details
vascular endothelial growth factor 120(0,0,1,115) Details
desmin 104(0,0,0,104) Details
PPAR gamma 67(0,0,1,62) Details
CD117 65(0,0,0,65) Details
TIMP 1 62(0,0,0,62) Details
CD31 61(0,0,1,56) Details
angiotensin II 60(0,0,0,60) Details
IL 6 53(0,0,0,53) Details
NAIP 51(0,0,0,51) Details
IL 1beta 50(0,0,0,50) Details
SMA1 50(0,0,1,45) Details
beta catenin 47(0,0,0,47) Details
Cx43 44(0,0,0,44) Details
Myosin 43(0,0,1,38) Details
integrins 41(0,0,0,41) Details
bFGF 41(0,0,0,41) Details
Rho kinase 38(0,0,1,33) Details
interleukin 13 36(0,0,0,36) Details
PCNA 36(0,0,0,36) Details
Ki 67 35(0,0,2,25) Details
GFAP 33(0,0,0,33) Details
S100 31(0,0,2,21) Details
IL 10 29(0,0,0,29) Details
nestin 29(0,0,0,29) Details
heme oxygenase 1 29(0,0,0,29) Details
bcl 2 27(0,0,1,22) Details
Toll like receptor 4 26(0,0,0,26) Details
angiopoietin 1 26(0,0,0,26) Details
Hepatocyte growth factor 25(0,0,0,25) Details
endothelin 1 25(0,0,0,25) Details
SMAD2 25(0,0,2,15) Details
PI3K 24(0,0,1,19) Details
S1P 24(0,0,0,24) Details
CD56 23(0,0,1,18) Details
CK 5 23(0,0,0,23) Details
histone deacetylase (protein family or complex) 23(0,0,0,23) Details
Gremlin 22(0,0,0,22) Details
Secreted protein acidic and rich in cysteine 22(0,0,0,22) Details
CK7 22(0,0,0,22) Details
cytokeratin 22(0,0,0,22) Details
C met 21(0,0,0,21) Details
metalloproteinase 21(0,0,0,21) Details
albumin 20(0,0,0,20) Details
caveolin 1 20(0,0,0,20) Details
laminin (protein family or complex) 20(0,0,0,20) Details
RANTES 19(0,0,0,19) Details
decorin 19(0,0,0,19) Details
IP 10 19(0,0,0,19) Details
immunoglobulins (protein family or complex) 19(0,0,1,14) Details
PTEN 18(0,0,0,18) Details
AMBP 18(0,0,0,18) Details
CD90 17(0,0,0,17) Details
Sca 1 17(0,0,0,17) Details
myocardin related transcription factor A 17(0,0,0,17) Details
ICAM 1 17(0,0,0,17) Details
alanine aminotransferase 17(0,0,0,17) Details
HSP27 17(0,0,0,17) Details
Transcription Factor GATA 6 17(0,0,0,17) Details
STAT3 16(0,0,0,16) Details
JAK2 16(0,0,0,16) Details
neurofibromatosis type I 16(0,0,0,16) Details
thrombin 16(0,0,1,11) Details
CD45 16(0,0,0,16) Details
Flk 1 16(0,0,0,16) Details
caldesmon 16(0,0,0,16) Details
HDAC 15(0,0,0,15) Details
E selectin 15(0,0,0,15) Details
zona occludens 1 15(0,0,0,15) Details
chemokine 15(0,0,0,15) Details
TIMP 2 15(0,0,0,15) Details
AP 1 (protein family or complex) 15(0,0,1,10) Details
hASCs 15(0,0,0,15) Details
CRBP 15(0,0,0,15) Details
p16 INK4a 14(0,0,0,14) Details
CD99 14(0,0,1,9) Details
keratin 14 14(0,0,0,14) Details
interleukin (protein family or complex) 14(0,0,0,14) Details
stem cell growth factor 14(0,0,0,14) Details
transferase 14(0,0,0,14) Details
beta is 14(0,0,0,14) Details
IL12 (protein family or complex) 14(0,0,0,14) Details
Chloride intracellular channel 4 13(0,0,0,13) Details
MMP2 13(0,0,0,13) Details
ED1 13(0,0,0,13) Details
CK8 13(0,0,0,13) Details
matrix metalloproteinase 9 13(0,0,0,13) Details
ALK5 13(0,0,0,13) Details
CMT1A 12(0,0,2,2) Details
PDGFR 12(0,0,0,12) Details
Tenascin C 12(0,0,0,12) Details
CYBB 12(0,0,0,12) Details
PFGE 12(0,0,1,7) Details
interleukin 4 12(0,0,0,12) Details
CGRP 12(0,0,0,12) Details
IL 23 12(0,0,0,12) Details
insulin like growth factor binding protein 7 12(0,0,0,12) Details
chondroitin sulfate proteoglycan NG2 11(0,0,0,11) Details
interleukin 8 11(0,0,0,11) Details
smoothelin 11(0,0,0,11) Details
interleukin 33 11(0,0,0,11) Details
INI1 11(0,0,0,11) Details
CXCR4 11(0,0,0,11) Details
monocyte chemoattractant protein 1 11(0,0,0,11) Details
follistatin 11(0,0,0,11) Details
fractalkine 11(0,0,0,11) Details
Unc119 11(0,0,0,11) Details
interferon gamma 11(0,0,0,11) Details
leptin 11(0,0,0,11) Details
NFkappaB (protein family or complex) 11(0,0,0,11) Details
protein is 11(0,0,0,11) Details
activin A 11(0,0,0,11) Details
Tgfbr2 11(0,0,0,11) Details
PKCalpha 10(0,0,0,10) Details
tissue transglutaminase 10(0,0,0,10) Details
keratins (protein family or complex) 10(0,0,0,10) Details
SMARD1 10(0,0,0,10) Details
osteopontin 10(0,0,0,10) Details
Tra2 beta 10(0,0,0,10) Details
Gemin2 10(0,0,0,10) Details
SMA3 10(0,0,1,5) Details
MK2 10(0,0,0,10) Details
CB 2 10(0,0,0,10) Details
von Willebrand factor 10(0,0,0,10) Details
Cartilage oligomeric matrix protein 10(0,0,0,10) Details
lubricin 10(0,0,0,10) Details
Gemin3 10(0,0,0,10) Details
cytokeratins 10(0,0,0,10) Details
Shroom 10(0,0,0,10) Details
superoxide dismutase 10(0,0,0,10) Details
estrogen receptor 10(0,0,0,10) Details
cyclooxygenase 2 10(0,0,0,10) Details
aspartate aminotransferase 10(0,0,0,10) Details
tryptophan hydroxylase 10(0,0,0,10) Details
elastin 10(0,0,0,10) Details
Moesin 10(0,0,0,10) Details
hemoglobin (protein family or complex) 9(0,0,0,9) Details
Substance P 9(0,0,0,9) Details
activator protein 1 9(0,0,1,4) Details
MT1 9(0,0,0,9) Details
eotaxin 9(0,0,0,9) Details
S 100 protein (protein family or complex) 9(0,0,0,9) Details
GATA 4 9(0,0,0,9) Details
MYLK 9(0,0,0,9) Details
Bcl x 9(0,0,0,9) Details
integrin linked kinase 9(0,0,0,9) Details
STAT1 9(0,0,0,9) Details
epithelial membrane antigen 9(0,0,0,9) Details
bone morphogenetic protein 7 9(0,0,0,9) Details
Angiopoietin 2 9(0,0,0,9) Details
AE3 9(0,0,0,9) Details
inhibin alpha 9(0,0,1,4) Details
AE1 9(0,0,0,9) Details
alkaline phosphatase 8(0,0,0,8) Details
myo inositol oxygenase 8(0,0,0,8) Details
AT1 8(0,0,0,8) Details
plasminogen activator inhibitor 8(0,0,0,8) Details
RAGE 8(0,0,0,8) Details
Telomerase (protein family or complex) 8(0,0,0,8) Details
phosphatidylinositol 3 kinase (protein family or complex) 8(0,0,1,3) Details
androgen receptor 8(0,0,1,3) Details
CD105 8(0,0,0,8) Details
ClC 3 8(0,0,0,8) Details
adipose differentiation related protein 8(0,0,0,8) Details
COMT 8(0,0,0,8) Details
EIF5A2 8(0,0,0,8) Details
Kruppel like factor 4 8(0,0,0,8) Details
CD146 8(0,0,0,8) Details
angiogenin 8(0,0,0,8) Details
High mobility group box 1 8(0,0,0,8) Details
NRF2 8(0,0,0,8) Details
versican 8(0,0,0,8) Details
Palladin 8(0,0,0,8) Details
CK19 8(0,0,0,8) Details
CD16 8(0,0,0,8) Details
epithelial membrane protein 2 8(0,0,0,8) Details
ST2L 8(0,0,0,8) Details
PDGF A 8(0,0,0,8) Details
SOD1 8(0,0,0,8) Details
catalase 7(0,0,0,7) Details
Ciliary neurotrophic factor 7(0,0,0,7) Details
ERK2 7(0,0,0,7) Details
HK2 7(0,0,0,7) Details
myeloperoxidase 7(0,0,0,7) Details
P12 7(0,0,1,2) Details
GTPase 7(0,0,0,7) Details
NR1 7(0,0,0,7) Details
stem cell factor 7(0,0,0,7) Details
5 HT 2 7(0,0,0,7) Details
Hsp90 7(0,0,0,7) Details
adrenomedullin 7(0,0,0,7) Details
PDE5 7(0,0,0,7) Details
KH type splicing regulatory protein 7(0,0,0,7) Details
VEGF receptor 1 7(0,0,0,7) Details
periostin 7(0,0,0,7) Details
activated leukocyte cell adhesion molecule 7(0,0,0,7) Details
chymase 7(0,0,0,7) Details
MEF2 7(0,0,0,7) Details
DLL4 7(0,0,0,7) Details
CD83 7(0,0,1,2) Details
ZNF265 7(0,0,0,7) Details
VAPB 7(0,0,0,7) Details
Plastin 3 7(0,0,0,7) Details
hTERT 7(0,0,0,7) Details
myosins (protein family or complex) 7(0,0,1,2) Details
CD10 7(0,0,0,7) Details
interleukin 15 7(0,0,0,7) Details
HLA (protein family or complex) 7(0,0,1,2) Details
BMP4 7(0,0,0,7) Details
hnRNP Q 7(0,0,0,7) Details
activin receptor like kinase 1 7(0,0,0,7) Details
Her 2 neu 7(0,0,0,7) Details
MAT2A 7(0,0,0,7) Details
transient receptor potential vanilloid 1 7(0,0,0,7) Details
serum response factor 7(0,0,0,7) Details
Par 3 7(0,0,0,7) Details
a collagen 7(0,0,0,7) Details
hypoxia inducible factor 1alpha 7(0,0,0,7) Details
JAK1 7(0,0,0,7) Details
lipase 7(0,0,1,2) Details
lysozyme 6(0,0,0,6) Details
glucagon like peptide 2 6(0,0,0,6) Details
GABA B receptors 6(0,0,0,6) Details
protein kinase C (protein family or complex) 6(0,0,0,6) Details
interferon (protein family or complex) 6(0,0,0,6) Details
plasminogen 6(0,0,0,6) Details
zinc finger protein 6(0,0,1,1) Details
ubiquitin 6(0,0,0,6) Details
CCR5 6(0,0,0,6) Details
cyclin E 6(0,0,0,6) Details
helicase 6(0,0,0,6) Details
apolipoprotein E 6(0,0,0,6) Details
FVIII 6(0,0,0,6) Details
angiotensin converting enzyme 2 6(0,0,0,6) Details
EGFR 6(0,0,0,6) Details
TRPV4 6(0,0,0,6) Details
melan A 6(0,0,0,6) Details
heat shock protein 72 6(0,0,0,6) Details
HDAC4 6(0,0,0,6) Details
endothelial nitric oxide synthase 6(0,0,0,6) Details
gelsolin 6(0,0,0,6) Details
Gemin4 6(0,0,0,6) Details
CLIP 6(0,0,0,6) Details
MRP8 6(0,0,0,6) Details
neuronal apoptosis inhibitory protein 6(0,0,0,6) Details
URG11 6(0,0,0,6) Details
Twist1 6(0,0,0,6) Details
forkhead transcription factor FOXL2 6(0,0,0,6) Details
profilin (protein family or complex) 6(0,0,0,6) Details
SOCS 3 6(0,0,0,6) Details
receptor tyrosine kinase 6(0,0,0,6) Details
PRDX6 6(0,0,0,6) Details
FMRP 6(0,0,0,6) Details
IkappaB kinase 6(0,0,1,1) Details
Stathmin 6(0,0,0,6) Details
immunophilin 6(0,0,1,1) Details
TN C 6(0,0,0,6) Details
synaptophysin 6(0,0,0,6) Details
CX3CR1 6(0,0,0,6) Details
signal transducer and activator of transcription 6 6(0,0,0,6) Details
Pin 1 6(0,0,0,6) Details
Fas associated death domain protein 6(0,0,1,1) Details
Galectin 3 6(0,0,0,6) Details
myosin phosphatase target subunit 1 6(0,0,0,6) Details
platelet endothelial cell adhesion molecule 1 6(0,0,0,6) Details
brains 6(0,0,0,6) Details
lactate dehydrogenase (protein family or complex) 5(0,0,0,5) Details
TAK1 5(0,0,0,5) Details
c Jun N terminal kinase (protein family or complex) 5(0,0,0,5) Details
acetylcholine receptor (protein family or complex) 5(0,0,0,5) Details
arginine vasopressin 5(0,0,0,5) Details
fibroblast growth factor 8 5(0,0,0,5) Details
erythropoietin 5(0,0,0,5) Details
c reactive protein 5(0,0,0,5) Details
progesterone receptor 5(0,0,0,5) Details
CD14 5(0,0,0,5) Details
KLF6 5(0,0,0,5) Details
FSGS 5(0,0,0,5) Details
SM1 5(0,0,0,5) Details
thrombospondin 1 5(0,0,0,5) Details
cytokeratin 18 5(0,0,0,5) Details
CHOP 5(0,0,0,5) Details
peroxisome proliferator activated receptor 5(0,0,0,5) Details
N cadherin 5(0,0,0,5) Details
interferon beta 5(0,0,0,5) Details
phosphoglycerate kinase 1 5(0,0,0,5) Details
CD70 5(0,0,0,5) Details
Vinculin 5(0,0,0,5) Details
SCO2 5(0,0,0,5) Details
crm 1 5(0,0,0,5) Details
SERPINE2 5(0,0,0,5) Details
Egr 1 5(0,0,0,5) Details
SMAD1 5(0,0,0,5) Details
neuron specific enolase 5(0,0,0,5) Details
PDE1A 5(0,0,0,5) Details
BAF180 5(0,0,0,5) Details
Sphingosine kinase 1 5(0,0,0,5) Details
LPA1 receptor 5(0,0,0,5) Details
FIZZ1 5(0,0,0,5) Details
SM22 5(0,0,0,5) Details
Smad 7 5(0,0,0,5) Details
COL1A1 5(0,0,0,5) Details
FSP1 5(0,0,0,5) Details
Fyn 5(0,0,0,5) Details
CD44 5(0,0,0,5) Details
Nopp140 5(0,0,0,5) Details
Notch 1 5(0,0,0,5) Details
PGP9.5 5(0,0,0,5) Details
CD35 5(0,0,0,5) Details
Toll like receptor 3 5(0,0,0,5) Details
Hsp70 5(0,0,0,5) Details
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Node List

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