| Name | HK2 |
|---|---|
| Synonyms | HK2; HOOK 2; HOOK2; Hook homolog 2; Hook2 protein; h hook2; hHK2; hook homolog 2 (Drosophila)… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20349724 | Zhou J, Wang F, Lu H, Zhang Y: [Impact of salvianolic acid-B on TGF-beta1-induced HK-2 epithelial-mesenchymal transition]. Zhongguo Zhong Yao Za Zhi. 2010 Jan;35(1):89-93. OBJECTIVE: To investigate the effect of salvianolic-acid B (SA-B) on epithelia-mesenchymal transition in human renal proximal tubular cells (HK2), induced by transforming growth factor beta1 (TGF-beta1). |
4(0,0,0,4) | Details |
| 18455002 | Carvajal G, Droguett A, Burgos ME, Aros C, Ardiles L, Flores C, Carpio D, Ruiz-Ortega M, Egido J, Mezzano S: Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy. Transplant Proc. 2008 Apr;40(3):734-9. In cultured human tubuloepithelial cells (HK2 cell line), Gremlin induction by TGF-beta was studied by confocal microscopy. |
2(0,0,0,2) | Details |
| 19900406 | Du R, Huang C, Bi Q, Zhai Y, Xia L, Liu J, Sun S, Fan D: URG11 mediates hypoxia-induced epithelial-to-mesenchymal transition by modulation of E-cadherin and beta-catenin. Biochem Biophys Res Commun. 2010 Jan 1;391(1):135-41. Epub 2009 Nov 11. Overexpression of URG11 in a human proximal tubule cell line (HK2) promoted a mesenchymal phenotype accompanied by reduced expression of the epithelial marker E-cadherin and increased expression of the mesenchymal markers vimentin and alpha-SMA, while URG11 knockdown by siRNA effectively reversed hypoxia-induced EMT. |
1(0,0,0,1) | Details |