Protein Information

Name SOD1
Synonyms ALS; ALS 1; ALS1; IPOA; Indophenoloxidase A; SOD; SOD 1; SOD1…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19332122 Turner BJ, Parkinson NJ, Davies KE, Talbot K: Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model. Neurobiol Dis. 2009 Jun;34(3):511-7. Epub 2009 Mar 28.


Mutations in the ubiquitously expressed survival motor neuron 1 (SMN1) and superoxide dismutase 1 (SOD1) genes are selectively lethal to motor neurons in spinal muscular atrophy (SMA) and familial amyotrophic lateral sclerosis (ALS), respectively.
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17964281 Zou T, Ilangovan R, Yu F, Xu Z, Zhou J: SMN protects cells against mutant SOD1 toxicity by increasing chaperone activity. Biochem Biophys Res Commun. 2007 Dec 28;364(4):850-5. Epub 2007 Oct 25.

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