Protein Information

Name androgen receptor
Synonyms AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
18537606 Echaniz-Laguna A, Bousiges O, Loeffler JP, Boutillier AL: Histone deacetylase inhibitors: therapeutic agents and research tools for deciphering motor neuron diseases. Curr Med Chem. 2008;15(13):1263-73.

The use of HDACi and possible mechanisms of action will be reviewed in three MND, i.e. amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and spinal and bulbar muscular atrophy (SBMA), diseases among which clinical trials with HDACi are currently perfomed (ALS, SMA).
6(0,0,1,1) Details
19614993 Hafezi-Bakhtiari S, Al-Habeeb A, Ghazarian D: Benign mixed tumor of the skin, hypercellular variant: a case report. J Cutan Pathol. 2009 Jul 10.


Immunohistochemical studies revealed positive immunoreactivity for EMA, CEA, CD117, HWMK, LWMK, CK7, Androgen receptor and S100 in the ductal (epithelial) cells and positive immunereactivity for calponin, SMA, CK 5/6 and p63 in the myoepithelial component.
1(0,0,0,1) Details
19338748 Yang R, Huang YC, Lin G, Wang G, Hung S, Dai YT, Sun ZY, Lue TF, Lin CS: Lack of direct androgen regulation of PDE5 expression. Biochem Biophys Res Commun. 2009 Mar 20;380(4):758-62. Epub 2009 Jan 29.


Androgen receptor (AR) expression was increased while PDE5 expression remained unchanged in DHT-treated rat cavernous smooth muscle cells (CSMC).
1(0,0,0,1) Details