| Name | MMP2 |
|---|---|
| Synonyms | 72 kDa gelatinase; 72 kDa type IV collagenase; 72 kDa type IV collagenase precursor; CLG 4; CLG4; CLG4A; Collagenase type 4A; Gelatinase A… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18029545 | Munoz-Luque J, Ros J, Fernandez-Varo G, Tugues S, Morales-Ruiz M, Alvarez CE, Friedman SL, Arroyo V, Jimenez W: Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats. J Pharmacol Exp Ther. 2008 Feb;324(2):475-83. Epub 2007 Nov 20. At the end of treatment, mean arterial pressure and portal pressure were measured, and liver samples were obtained to evaluate infiltrate of mononuclear cells, hepatic apoptosis, alpha-smooth muscle actin (SMA) expression, collagen content, and matrix metalloproteinase (MMP)-2 abundance in all animals. |
1(0,0,0,1) | Details |
| 20034937 | Schweitzer M, Mitmaker B, Obrand D, Sheiner N, Abraham C, Dostanic S, Meilleur M, Sugahara T, Chalifour LE: modulates matrix metalloproteinase expression, activity, and signaling in abdominal aortic aneurysms. Vasc Endovascular Surg. 2010 Feb;44(2):116-22. Epub 2009 Dec 23. Matrix metalloproteinase 1, MMP2, MMP3, MMP9, Tissue Inhibitor of Metalloproteinase (TIMP2), TIMP3, TIMP4, or total Sma Mothers Against Decapentaplegia (SMAD2) expression did not differ with treatment. There was a trend toward reduced MMP8 and TIMP1 expression and MMP2 zymographic activity in the AT-treatment group. |
1(0,0,0,1) | Details |
| 19175832 | Lin YL, Wu CF, Huang YT: Effects of rhubarb on migration of rat hepatic stellate cells. J Gastroenterol Hepatol. 2009 Mar;24(3):453-61. Epub 2008 Oct 23. Matrix metalloproteinase (MMP)-2 activity was examined by gelatin zymography. |
1(0,0,0,1) | Details |
| 20348013 | Saad S, Stanners SR, Yong R, Tang O, Pollock CA: NOTCH MEDIATED EPITHELIAL TO MESENCHYMAL TRANSFORMATION IS ASSOCIATED WITH INCREASED EXPRESSION OF THE SNAIL TRANSCRIPTION FACTOR. Int J Biochem Cell Biol. 2010 Mar 25. Matrix Metalloproteinase (MMP)-2 &-9 production were determined by zymography. |
1(0,0,0,1) | Details |
| 20038548 | Dalla Costa AP, Clemente CF, Carvalho HF, Carvalheira JB, Nadruz W Jr, Franchini KG: FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex. Cardiovasc Res. 2010 Jan 22. Proliferation (anti-5-bromo-2'- and anti-Ki67 nuclear labelling), differentiation into myofibroblasts (expression of alpha-smooth muscle actin-alpha-SMA), and the activity of matrix metalloproteinase-2 were equally enhanced in stretched NF-P3/80 and AF-P1/80. |
1(0,0,0,1) | Details |
| 18802012 | Hao Q, Liu J, Pappu R, Su H, Rola R, Gabriel RA, Lee CZ, Young WL, Yang GY: Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2151-7. Epub 2008 Sep 18. The function of BMDCs was further examined through matrix metalloproteinase (MMP)-2 and -9 activity. |
1(0,0,0,1) | Details |
| 18490073 | Schwettmann L, Wehmeier M, Jokovic D, Aleksandrova K, Brand K, Manns MP, Lichtinghagen R, Bahr MJ: Hepatic expression of A disintegrin and metalloproteinase (ADAM) and ADAMs with thrombospondin motives (ADAM-TS) enzymes in patients with chronic liver diseases. J Hepatol. 2008 Aug;49(2):243-50. Epub 2008 Apr 24. METHODS: Seventy-one biopsy samples from patients with chronic liver diseases were analyzed for mRNA expression of ADAM-8, -9, -12, -28, -TS1, -TS2, matrix metalloprotease (MMP)-2, -9 and tissue inhibitor of metalloproteinases-1 and -2 by quantitative real-time RT-PCR. |
1(0,0,0,1) | Details |
| 20143336 | Lee TF, Mak KM, Rackovsky O, Lin YL, Kwong AJ, Loke JC, Friedman SL: Downregulation of hepatic stellate cell activation by and mediated by adipose differentiation-related protein (ADRP). J Cell Physiol. 2010 Feb 8;223(3):648-657. Furthermore, ADRP induction by and resulted in decreased expression of collagen I and matrix metalloproteinase-2 mRNA, fibrogenic genes associated with activated HSCs, while increasing matrix metalloproteinase-1 mRNA; ADRP knockdown with siRNA reversed these changes. |
1(0,0,0,1) | Details |
| 19096916 | Fregnani ER, Sobral LM, Alves FA, Soares FA, Kowalski LP, Coletta RD: Presence of myofibroblasts and expression of matrix metalloproteinase-2 (MMP-2) in ameloblastomas correlate with rupture of the osseous cortical. Pathol Oncol Res. 2009 Jun;15(2):231-40. Epub 2008 Dec 19. |
2(0,0,0,2) | Details |
| 19670427 | Tong Z, Chen R, Alt DS, Kemper S, Perbal B, Brigstock DR: Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. Hepatology. 2009 Sep;50(3):939-47. Moreover, CCl (4)-induced serum hepatic tissue levels of alpha-SMA or acid-soluble collagen, and messenger RNA expression of alpha-SMA, collagen alpha1 (I), matrix metalloprotease-2, or tissue inhibitor of metalloprotease-1 were greater in transgenic mice than in wild-type mice. |
1(0,0,0,1) | Details |
| 18317806 | Maeda T, Hashitani S, Zushi Y, Segawa E, Tanaka N, Sakurai K, Urade M: Establishment of a nude mouse transplantable model of a human malignant fibrous histiocytoma of the mandible with high metastatic potential to the lung. J Cancer Res Clin Oncol. 2008 Sep;134(9):1005-11. Epub 2008 Mar 4. In MFH-NC, the expressions of MMP7, MMP9, MT1-MMP, CXCR4, COX-2 and integrin alpha4 were up-regulated, while those of MMP2 and TIMP1 were down-regulated. |
1(0,0,0,1) | Details |
| 20155461 | Shou Z, Shen L, Xiong P: Assessing the validity of a novel model of vertebral artery type of cervical syndrome induced by injecting sclerosing agent next to transverse process of cervical vertebra. J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):85-8. Epub 2010 Feb 14. Transcranial Doppler (TCD) was used to detect the average speed of blood (Vm), pulsatility index (Pi) and the resistant index (Ri) of the vertebral artery, hematoxylin and eosin (HE) staining was used to observe the morphological changes, and immunohistochemistry was used to detect the expression of alpha-smooth muscle actin (alpha-SMA) and matrix metalloproteinase-2 (MMP-2). |
1(0,0,0,1) | Details |