| Name | phosphatidylinositol 3 kinase (protein family or complex) |
|---|---|
| Synonyms | PI3 kinase; PI3 kinases; PI3K; Phosphatidylinositol 3 kinase; Phosphatidylinositol 3 kinases; Phosphatidylinositol 4,5 bisphosphate 3 kinase; Phosphatidylinositol 4,5 bisphosphate 3 kinases |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19271115 | Masamune A, Shimosegawa T: Signal transduction in pancreatic stellate cells. J Gastroenterol. 2009;44(4):249-60. Epub 2009 Mar 7. Signaling molecules, such as peroxisome proliferator-activated receptor-gamma (PPAR-gamma), Rho/Rho kinase, nuclear factor-kappaB (NF-kappaB), mitogen-activated protein (MAP) kinases, phosphatidylinositol 3 kinase (PI3K), Sma- and Mad-related proteins, and reactive species (ROS) might be candidates for the development of anti-fibrosis therapy targeting PSCs. |
6(0,0,1,1) | Details |
| 20015942 | Lee YJ, Han HJ: Troglitazone ameliorates high glucose-induced EMT and dysfunction of SGLTs through PI3K/Akt, GSK-3{beta}, Snail1, and {beta}-catenin in renal proximal tubule cells. Am J Physiol Renal Physiol. 2009 Dec 16. HG stimulated the production of cellular reactive species (ROS) and antioxidant blocked HG-induced increase in phosphatidylinositol 3-kinase (PI3K)/Akt activation. |
1(0,0,0,1) | Details |
| 18579759 | He J, Bazan HE: Epidermal growth factor synergism with TGF-beta1 via PI-3 kinase activity in corneal keratocyte differentiation. Invest Ophthalmol Vis Sci. 2008 Jul;49(7):2936-45. Inhibition of EGF-R activation and of the phosphatidylinositol-3 kinase (PI-3K)/Akt-1 pathway prevented the action of EGF on TGF-beta1 cell differentiation. |
1(0,0,0,1) | Details |