| Name | protein is |
|---|---|
| Synonyms | ANX 2; p36; LIP 2; LIP2; ANX2; ANX2L4; ANX2P1; ANX2P2… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18662980 | Rudnik-Schoneborn S, Heller R, Berg C, Betzler C, Grimm T, Eggermann T, Eggermann K, Wirth R, Wirth B, Zerres K: Congenital heart disease is a feature of severe infantile spinal muscular atrophy. J Med Genet. 2008 Oct;45(10):635-8. Epub 2008 Jul 28. Our findings suggest that the SMN protein is relevant for normal cardiogenesis. |
1(0,0,0,1) | Details |
| 17825142 | Guo W, Xu H, Huang WY, Chen J, Yang Y, Fu R, Liu HM, Zha XL, Zhang ZG: [Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1]. Zhonghua Yi Xue Za Zhi. 2007 Jun 26;87(24):1660-5. CONCLUSION: PHB protein is expressed in the normal renal tissues and adversely correlated with the degree of tubulointerstitial lesions. |
1(0,0,0,1) | Details |
| 20176735 | Wen HL, Lin YT, Ting CH, Lin-Chao S, Li H, Hsieh-Li HM: Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy. Hum Mol Genet. 2010 Feb 25. |
1(0,0,0,1) | Details |
| 18036582 | Foehr ML, Liu J: Dorsoventral patterning of the C. elegans postembryonic mesoderm requires both LIN-12/Notch and TGFbeta signaling. Dev Biol. 2008 Jan 1;313(1):256-66. Epub 2007 Oct 25. We have previously shown that mutations in the Schnurri homolog sma-9 cause ventralization of the M lineage and that wild-type SMA-9 antagonizes the Sma/Mab TGFbeta pathway to promote dorsal M lineage fates [Foehr, M.L., Lindy, A.S., Fairbank, R.C., Amin, N.M., Xu, M., Yanowitz, J., Fire, A.Z., Liu, J., 2006. We have found that although LIN-12 protein is present in both the dorsal and ventral M lineage cells, its ligands LAG-2 and APX-1 are asymmetrically localized in cells adjacent to ventral M-derived cells, and may function redundantly in promoting ventral M lineage fates. |
1(0,0,0,1) | Details |
| 19445707 | Wu CY, Gomez-Curet I, Funanage VL, Scavina M, Wang W: Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent. BMC Cell Biol. 2009 May 16;10:40. The SMN protein is known to play a role in RNA metabolism, neurite outgrowth, and cell survival. |
1(0,0,0,1) | Details |
| 20201562 | Shafey D, Boyer JG, Bhanot K, Kothary R: Identification of Novel Interacting Protein Partners of SMN Using Tandem Affinity Purification. J Proteome Res. 2010 Mar 4. We have identified a number of novel SMN interacting proteins in both C2C12 and PC12 cells, and from among these we have validated Annexin II and myosin regulatory light chain (MRLC). |
1(0,0,0,1) | Details |
| 19703128 | Hao LS, Zhang XL, An JY, Karlin J, Tian XP, Dun ZN, Xie SR, Chen S: PTEN expression is down-regulated in liver tissues of rats with hepatic fibrosis induced by biliary stenosis. APMIS. 2009 Sep;117(9):681-91. In conclusion, expression of PTEN mRNA and protein is down-regulated in fibrogenic rat liver tissue, and its expression in HSC in vivo also decreases with progression of fibrosis. |
1(0,0,0,1) | Details |
| 19735367 | Clelland AK, Kinnear NP, Oram L, Burza J, Sleeman JE: The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells. Traffic. 2009 Nov;10(11):1585-98. Epub 2009 Aug 4. |
1(0,0,0,1) | Details |
| 18093976 | Piazzon N, Rage F, Schlotter F, Moine H, Branlant C, Massenet S: In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein. J Biol Chem. 2008 Feb 29;283(9):5598-610. Epub 2007 Dec 19. Then, by in vitro experiments, we demonstrated that the SMN protein is essential for this association. |
1(0,0,0,1) | Details |
| 18689355 | Walker MP, Rajendra TK, Saieva L, Fuentes JL, Pellizzoni L, Matera AG: SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain. Hum Mol Genet. 2008 Nov 1;17(21):3399-410. Epub 2008 Aug 8. The human SMN protein is part of a large macromolecular complex involved in the biogenesis of small ribonucleoproteins. |
1(0,0,0,1) | Details |
| 18485868 | Zhang Z, Lotti F, Dittmar K, Younis I, Wan L, Kasim M, Dreyfuss G: SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell. 2008 May 16;133(4):585-600. The survival of motor neurons (SMN) protein is essential for the biogenesis of small nuclear RNA (snRNA)-ribonucleoproteins (snRNPs), the major components of the pre-mRNA splicing machinery. |
1(0,0,0,1) | Details |