Name | vascular endothelial growth factor |
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Synonyms | VEGF; VEGF A; VEGFA; VPF; Vascular endothelial growth factor A; Vascular endothelial growth factor A precursor; Vascular permeability factor; vascular endothelial growth factor… |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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18980821 | Saito T, Yamamoto Y, Matsumura T, Fujimura H, Shinno S: Serum levels of vascular endothelial growth factor elevated in patients with muscular dystrophy. Brain Dev. 2009 Sep;31(8):612-7. Epub 2008 Nov 5. |
7(0,0,0,7) | Details |
19093260 | Hornychova H, Melichar B, Tomsova M, Mergancova J, Urminska H, Ryska A: Tumor-infiltrating lymphocytes predict response to neoadjuvant chemotherapy in patients with breast carcinoma. Cancer Invest. 2008 Dec;26(10):1024-31. In the remaining 63 patients, a significant decrease in the percentage of Ki-67, vascular endothelial growth factor expression, CD68 (+) monocytes, and increased CD31 (+), CD34 (+), and SMA (+) stromal vessels, maximal CD3 (+) and CD56 (+) lymphocyte, maximal and mean CD83 (+) cell, maximal CD1a (+), and maximal and mean S100 (+) cell counts were observed after neoadjuvant chemotherapy. |
6(0,0,1,1) | Details |
20177148 | Jeon ES, Heo SC, Lee IH, Choi YJ, Park JH, Choi KU, Park DY, Suh DS, Yoon MS, Kim JH: Ovarian Cancer-Derived Lysophosphatidic Acid Stimulates Secretion of VEGF and SDF-1a from Human Mesenchymal Stem Cells. Exp Mol Med. 2010 Feb 22. |
5(0,0,0,5) | Details |
18339868 | Dang DT, Chun SY, Burkitt K, Abe M, Chen S, Havre P, Mabjeesh NJ, Heath EI, Vogelzang NJ, Cruz-Correa M, Blayney DW, Ensminger WD, St Croix B, Dang NH, Dang LH: Hypoxia-inducible factor-1 target genes as indicators of tumor vessel response to vascular endothelial growth factor inhibition. Cancer Res. 2008 Mar 15;68(6):1872-80. |
5(0,0,0,5) | Details |
19434519 | Zhang ZB, Cai L, Zheng SG, Xiong Y, Dong JH: Overexpression of caveolin-1 in hepatocellular carcinoma with metastasis and worse prognosis: correlation with vascular endothelial growth factor, microvessel density and unpaired artery. Pathol Oncol Res. 2009 Sep;15(3):495-502. Epub . |
4(0,0,0,4) | Details |
18177424 | Ruger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hocker P, Dettke M: Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation. 2008 Sep;76(7):772-83. Epub 2008 Jan 3. The culture of unselected BMMNC in 3D fibrin matrices led to the formation of cell clusters expressing the endothelial progenitor cell (EPC) markers CD133, CD34, vascular endothelial growth factor receptor (VEGFR)-2, and c-kit, with stellar shaped spreading of peripheral elongated cells forming tube-like structures with increasing complexity over time. |
1(0,0,0,1) | Details |
17909053 | Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, Struett C, Nguyen KN, Kim G, Tihan T, Bao Y, Brekken RA, Bergers G, Folkman J, Weiss WA: Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Res. 2007 Oct 1;67(19):9435-42. Tumor cells were proliferative, secreted high levels of the angiogenic ligand vascular endothelial growth factor (VEGF), and recruited a complex vasculature expressing the angiogenic markers VEGF-R2, alpha-SMA, and matrix metalloproteinases MMP-2 and MMP-9, all of which are also expressed in human disease. |
1(0,0,0,1) | Details |
19080229 | He CM, Zheng FL, Liu YP: [The effects of mycophenolate mofetil on renal interstitial fibrosis and epithelial-myofibroblast translation in -induced renal failure rats]. Zhonghua Nei Ke Za Zhi. 2008 Nov;47(11):901-5. OBJECTIVE: The aim of this study is to examine the effect of mycophenolate mofetil (MMF) on epithelial-myofibroblast translation (EMT) in -induced chronic renal failure (CRF) rat model and the role of vascular endothelial growth factor (VEGF) and inhibitor of differentiation (Id2 and Id3) in EMT in the rat kidney. |
4(0,0,0,4) | Details |
18355371 | Nonaka M, Pawankar R, Fukumoto A, Yagi T: Heterogeneous response of nasal and lung fibroblasts to transforming growth factor-beta 1. Clin Exp Allergy. 2008 May;38(5):812-21. Epub 2008 Mar 18. OBJECTIVE: We examined whether there is any heterogeneity between nasal and lung fibroblasts upon stimulation with TGF-beta (1) with regard to the synthesis of SMA, pro-collagen type I and vascular endothelial growth factor (VEGF) as well as translocation of Smad proteins. |
4(0,0,0,4) | Details |
19800207 | Meller R, Schiborra F, Brandes G, Knobloch K, Tschernig T, Hankemeier S, Haasper C, Schmiedl A, Jagodzinski M, Krettek C, Willbold E: Postnatal maturation of tendon, cruciate ligament, meniscus and articular cartilage: a histological study in sheep. Ann Anat. 2009 Dec;191(6):575-85. Epub 2009 Sep 4. Also, staining of alpha-smooth muscle actin (SMA) and vascular endothelial growth factor (VEGF) steadily decreased. |
1(0,0,0,1) | Details |
18344448 | Kaempf S, Johnen S, Salz AK, Weinberger A, Walter P, Thumann G: Effects of bevacizumab (Avastin) on retinal cells in organotypic culture. Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3164-71. Epub 2008 Mar 14. The increased expression of SMA is an indication of the loss of functional VEGF modulating smooth muscle cells in mature vessels. |
1(0,0,0,1) | Details |
19134051 | Vanheule E, Geerts AM, Van Huysse J, Schelfhout D, Praet M, Van Vlierberghe H, De Vos M, Colle I: An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis. Int J Exp Pathol. 2008 Dec;89(6):419-32. Thereafter, liver samples were taken for sirius red, CD31, Ki67, vascular endothelial growth factor (VEGF) and alpha-smooth muscle actin (alpha-SMA) evaluation by immunohistochemistry (IHC). |
3(0,0,0,3) | Details |
18498544 | Ahn MH, Park BJ, Kwon JH, An SH, Park JW, Jang AS, Rhim T, Park CS: Asp-Tyr-inhibits airway inflammation in toluene-2,4-diisocyanate-induced asthma mice. Clin Exp Allergy. 2008 Jun;38(6):1025-32. The changes of cell number and the level of vascular endothelial growth factor (VEGF) in bronchoalveolar lavage (BAL) fluid and response to methacholine (MCh) were measured using the in vivo TDI-sensitized/challenged mice model. |
- tetrapeptide 3(0,0,0,3) | Details |
18802012 | Hao Q, Liu J, Pappu R, Su H, Rola R, Gabriel RA, Lee CZ, Young WL, Yang GY: Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages. Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2151-7. Epub 2008 Sep 18. OBJECTIVE: We investigated the role of bone marrow-derived cells (BMDCs) in an angiogenic focus, induced by VEGF stimulation. |
3(0,0,0,3) | Details |
19114984 | Liu Y, Lui EL, Friedman SL, Li L, Ye T, Chen Y, Poon RT, Wo J, Kok TW, Fan ST: PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Lab Invest. 2009 Feb;89(2):209-21. Epub 2008 Dec 29. |
3(0,0,0,3) | Details |
17822316 | Raica M, Cimpean AM, Anghel A: Immunohistochemical expression of vascular endothelial growth factor (VEGF) does not correlate with microvessel density in renal cell carcinoma. Neoplasma. 2007;54(4):278-84. The aim of present study was to investigate the relationship between the immunohistochemical expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) assessed by CD31 and endoglin (CD105) in renal cell carcinoma (RCC). |
3(0,0,0,3) | Details |
19929197 | Takeuchi H, Hashimoto N, Kitai R, Kubota T, Kikuta KI: Proliferation of vascular smooth muscle cells in glioblastoma multiforme. . J Neurosurg. 2009 Nov 20. In GBMs, the contribution of VSMCs in angiogenesis accompanying endothelial proliferation and the correlation of VSMC proliferation with vascular endothelial growth factor (VEGF) expression were examined using an immunohistochemical method. |
3(0,0,0,3) | Details |
18689869 | Tabatabai G, Herrmann C, von Kurthy G, Mittelbronn M, Grau S, Frank B, Mohle R, Weller M, Wick W: VEGF-dependent induction of CD62E on endothelial cells mediates glioma tropism of adult haematopoietic progenitor cells. Brain. 2008 Oct;131(Pt 10):2579-95. Epub 2008 Aug 9. |
3(0,0,0,3) | Details |
17965528 | Morishita C, Jin E, Kikuchi M, Egawa S, Fujiwara M, Ohaki Y, Ghazizadeh M, Takemura T, Kawanami O: Angiogenic switching in the alveolar capillaries in primary lung adenocarcinoma and squamous cell carcinoma. J Nippon Med Sch. 2007 Oct;74(5):344-54. We applied the TdT-mediated nick-end labeling assay and the reverse transcription-polymerase chain reaction for vascular endothelial growth factor (VEGF) and its receptors (VEGFRs). |
3(0,0,0,3) | Details |
18384688 | Pavlakis K, Messini I, Vrekoussis T, Yiannou P, Keramopoullos D, Louvrou N, Liakakos T, Stathopoulos EN: The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions. BMC Cancer. 2008 Apr 2;8:88. METHODS: 78 in situ ductal carcinomas of all degrees of differentiation, 22 atypical ductal hyperplasias, 25 in situ lobular carcinomas, 18 atypical lobular hyperplasias, 32 ductal epithelial hyperplasias of usual type and 8 flat atypias were immunohistochemically investigated for the expression of vascular endothelial growth factor (VEGF), smooth muscle actin (SMA) and CD34, while microvessel density (MVD) was counted using the anti-CD31 antibody. |
2(0,0,0,2) | Details |
19180920 | He CM, Zheng FL, Lian YG, Liu YP: [Relationship between the effect of vascular endothelial growth factor on epithelial-mesenchymal transition of HK-2 cells and the expressions of bone morphogenetic protein-7 and inhibitor of DNA binding/differentiation]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008 Dec;30(6):703-10. |
2(0,0,0,2) | Details |
19567053 | Li C, Zhang B, Wang ZH, Chen JC, Li B, Wang SX, Chen J, Li CH, Wang W, Song YF: [Significance of a reversal expression of the angiopoietin-1 and 2 in oral squamous cell carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 May;44(5):412-8. METHODS: The expression of Ang-1, Ang-2, vascular endothelial growth factor (VEGF), CD34 and alpha-smooth muscle actin (alpha-SMA) were studied in 62 human OSCCs, 30 adjacent noncancerous oral tissues and 10 normal oral mucosa by conventional immunohistochemistry. |
2(0,0,0,2) | Details |
19023579 | Meller R, Brandes G, Drogemuller C, Fritz F, Schiborra F, Fehr M, Hankemeier S, Krettek C, Hurschler C: Graft remodeling during growth following anterior cruciate ligament reconstruction in skeletally immature sheep. Arch Orthop Trauma Surg. 2009 Aug;129(8):1037-46. Epub 2008 Nov 21. Each group was characterised histomorphometrically, by immunostaining (VEGF, SMA), by transmission electron microscopy (TEM) and biomechanically (UFS Roboter). |
2(0,0,0,2) | Details |
17674035 | Budny T, Palmes D, Stratmann U, Minin E, Herbst H, Spiegel HU: Morphologic features in the regenerating liver--a comparative intravital, lightmicroscopical and ultrastructural analysis with focus on hepatic stellate cells. Virchows Arch. 2007 Oct;451(4):781-91. Epub 2007 Aug 3. Morphological features were investigated by light microscopy, immunohistochemistry [alpha-smooth muscle actin (alpha-SMA), Desmin, vascular endothelial growth factor (VEGF)/VEGF receptor, Ki-67, ssDNA], intravital microscopy (sinusoid density, number of hepatocytes, and HSC), and electron microscopy focussed on cell-to-cell interactions. |
2(0,0,0,2) | Details |
18044793 | Su H, Yeghiazarians Y, Lee A, Huang Y, Arakawa-Hoyt J, Ye J, Orcino G, Grossman W, Kan YW: AAV serotype 1 mediates more efficient gene transfer to pig myocardium than AAV serotype 2 and plasmid. J Gene Med. 2008 Jan;10(1):33-41. We injected CMVLacZ and CMVVEGF (vectors with the cytomegalovirus (CMV) promoter driving LacZ and VEGF gene expression) unpackaged or packaged in AAV serotypes 1 or 2 capsids into pig myocardium. |
2(0,0,0,2) | Details |
18477569 | Kihm LP, Wibisono D, Muller-Krebs S, Pfisterer F, Morath C, Gross ML, Morcos M, Seregin Y, Bierhaus A, Nawroth PP, Zeier M, Schwenger V: RAGE expression in the human peritoneal membrane. Nephrol Dial Transplant. 2008 Oct;23(10):3302-6. Epub 2008 May 13. The expression of CD3, IL-6, activated NFkappaBp65, VEGF, transforming growth factor (TGF)-beta1, smooth-muscle actin (SMA), (MGO) and RAGE was analysed immunohistochemically. |
2(0,0,0,2) | Details |
19683567 | Xu X, Kherada N, Hong X, Quan C, Zheng L, Wang A, Wold LE, Lippmann M, Chen LC, Rajagopalan S, Sun Q: Diesel exhaust exposure induces angiogenesis. Toxicol Lett. 2009 Dec 1;191(1):57-68. Epub 2009 Aug 14. In addition, WDE exposure significantly increased mRNA expression of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor (HIF)-1alpha, while decreasing prolylhydroxylase (PHD) 2 expression. |
2(0,0,0,2) | Details |
19393328 | Sugiura H, Ichikawa T, Liu X, Kobayashi T, Wang XQ, Kawasaki S, Togo S, Kamio K, Mao L, Ann Y, Ichinose M, Rennard SI: N-acetyl-inhibits TGF-beta1-induced profibrotic responses in fibroblasts. Pulm Pharmacol Ther. 2009 Dec;22(6):487-91. Epub 2009 Apr 22. OBJECTIVES: The aim of this study was to evaluate whether the antioxidant N-acetyl- (NAC) can affect TGF-beta (1)-mediated tissue remodeling in fibroblasts or modulate the production of fibronectin and vascular endothelial growth factor (VEGF) which are believed to be important mediators of tissue repair and remodeling. |
2(0,0,0,2) | Details |
19336420 | Ibba-Manneschi L, Manetti M, Milia AF, Miniati I, Benelli G, Guiducci S, Mecacci F, Mello G, Di Lollo S, Matucci-Cerinic M: Severe fibrotic changes and altered expression of angiogenic factors in maternal scleroderma: placental findings. Ann Rheum Dis. 2010 Feb;69(2):458-61. Epub 2009 Mar 30. The sections were stained with Masson's trichrome and phosphotungstic-acid-haematoxylin and immunostained for connective tissue growth factor (CTGF), alpha-smooth muscle actin (alpha-SMA), vascular endothelial growth factor (VEGF), placenta growth factor (PlGF) and receptors VEGFR-1 and VEGFR-2. |
2(0,0,0,2) | Details |
18476548 | Huang HM, Ma LL, Ren H, Wu SF, Jiang ZM: [Tissue-engineered graft constructed by bone marrow mononuclear cells and heterogeneous acellularized tissue matrix: an animal experiment]. Zhonghua Yi Xue Za Zhi. 2007 Dec 25;87(48):3440-2. METHODS: Mononuclear cells were isolated from the bone marrow from piglets and cultured in different mediums including either vessel endothelial growth factor (VEGF) or platelet derived growth factor BB (PDGF-BB) to observe the differentiation of cells. |
2(0,0,0,2) | Details |
19836061 | Alkafafy M, Elnasharty M, Sayed-Ahmed A, Abdrabou M: Immunohistochemical studies of the epididymal duct in Egyptian water buffalo (Bubalus bubalis). Acta Histochem. 2009 Oct 14. Primary antibodies against angiotensin converting enzyme (ACE), S-100, galactosyltransferase (GalTase), alpha smooth muscle actin (alpha-SMA), connexin 43 (Cx43) and vascular endothelial growth factor (VEGF) were used for immunohistochemical studies. |
2(0,0,0,2) | Details |
17571460 | Ke Q, Erbolat, Zhang HY, Bu H, Li S, Shi DN, Yang GH, Chen HJ, Wei B: Clinicopathologic features of pleomorphic hyalinizing angiectatic tumor of soft parts. Chin Med J. 2007 May 20;120(10):876-81. Immunohistochemical stains for vimentin, S-100 protein, CD34, CD31, CD99, VEGF, desmin, CD117, alpha-SMA, and MIB-1 were performed with the Envision system. |
2(0,0,0,2) | Details |
19968077 | Yu DX, Ma XX, Wei HG, Zhang XM, Wang Q, Li CF: [Angiogenesis and its maturation of hepatocellular carcinoma and its correlation with the deoxyhemoglobin parameters R2 * and T2 * values by using noninvasive magnetic resonance imaging]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2009 Oct;31(5):589-93. The expressions of VEGF, Flk-1, and PCNA index (PI) were evaluated. |
2(0,0,0,2) | Details |
20041970 | Khan M, Mohsin S, Khan SN, Riazuddin S: Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice. J Cell Mol Med. 2009 Dec 11. A decline in the tube-forming ability on Matrigel was also observed in aged MSCs as well as down-regulation of IGF-1, FGF-2, VEGF and HGF compared to young cells. |
2(0,0,0,2) | Details |
19716681 | Mueller CK, Lee SY, Schultze-Mosgau S: Characterization of interfacial reactions between connective tissue and allogenous implants used for subdermal soft tissue augmentation. Int J Oral Maxillofac Surg. 2009 Nov;38(11):1194-200. Epub 2009 Aug 28. After 7 or 14 days, tissue specimens were obtained and analyzed for transforming growth factor (TGF)-beta1 and vascular endothelial growth factor (VEGF) by immunoblotting as well as alpha-smooth muscle actin (SMA)-and endoglin (CD105)-expression by immunohistochemistry. |
2(0,0,0,2) | Details |
19721715 | Rasanen K, Virtanen I, Salmenpera P, Grenman R, Vaheri A: Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma. PLoS One. 2009 Sep 1;4(9):e6879. VEGF, HGF/SF and FGF7 mRNA levels were upregulated to variable degree in nemosis. |
1(0,0,0,1) | Details |
20067910 | Loureiro J, Schilte M, Aguilera A, Albar-Vizcaino P, Ramirez-Huesca M, Perez-Lozano ML, Gonzalez-Mateo G, Aroeira LS, Selgas R, Mendoza L, Ortiz A, Ruiz-Ortega M, van den Born J, Beelen RH, Lopez-Cabrera M: BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure. Nephrol Dial Transplant. 2010 Apr;25(4):1098-108. Epub 2010 Jan 12. METHODS: Epitheliod or non-epitheliod MC were analysed for the expression of BMP-7, TGF-beta1, activated Smads, epithelial cadherin (E-cadherin), collagen I, alpha smooth muscle cell actin (alpha-SMA) and vascular endothelial growth factor (VEGF) using standard procedures. |
1(0,0,0,1) | Details |
17997848 | Armah HB, Wilson NO, Sarfo BY, Powell MD, Bond VC, Anderson W, Adjei AA, Gyasi RK, Tettey Y, Wiredu EK, Tongren JE, Udhayakumar V, Stiles JK: Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J. 2007 Nov 12;6:147. Serum and CSF levels of 36 different biomarkers (IL-1beta, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17, Eotaxin, FGF basic protein, CRP, G-CSF, GM-CSF, IFN-gamma, TNF-alpha, IP-10, MCP-1 (MCAF), MIP-1alpha, MIP-1beta, RANTES, SDF-1alpha, CXCL11 (I-TAC), Fas-ligand [Fas-L], soluble Fas [sFas], sTNF-R1 (p55), sTNF-R2 (p75), MMP-9, TGF-beta1, PDGF bb and VEGF) were measured and the results compared between the 3 groups. |
1(0,0,0,1) | Details |
19786014 | Shi H, Dong L, Bai Y, Zhao J, Zhang Y, Zhang L: liver fibrosis in rats. Eur J Pharmacol. 2009 Nov 25;623(1-3):119-24. Epub 2009 Sep 26. As compared with the CGA-treated group, the expression of bcl-2, vascular endothelial growth factor (VEGF), and transforming growth factor (TGF-beta1) mRNA was increased in CCl (4) group, whereas Bax mRNA expression decreased. |
against carbon tetrachloride-induced 1(0,0,0,1) | Details |
20044951 | Lee SH, Leem HS, Jeong SM, Lee K: Bevacizumab accelerates corneal wound healing by inhibiting TGF-beta2 expression in alkali-burned mouse cornea. BMB Rep. 2009 Dec 31;42(12):800-5. This study investigated the effect of subconjunctival injections of bevacizumab, an anti-VEGF antibody, on processes involved in corneal wound healing after alkali burn injury. |
1(0,0,0,1) | Details |
20223267 | Kelm JM, Lorber V, Snedeker JG, Schmidt D, Broggini-Tenzer A, Weisstanner M, Odermatt B, Mol A, Zund G, Hoerstrup SP: A novel concept for scaffold-free vessel tissue engineering: Self-assembly of microtissue building blocks. J Biotechnol. 2010 Mar 17. The resulting vessels were analyzed by immunohistochemistry for extracellular matrix (ECM) and cell phenotype (von Willebrand factor, alpha-SMA, Ki67, VEGF). |
1(0,0,0,1) | Details |
19934363 | Dong H, Wang Q, Zhang Y, Jiang B, Xu X, Zhang Z: Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium. Exp Biol Med. 2009 Dec;234(12):1417-24. But, VEGF, as an early angiogenic cytokine, is inadequate for mediating histologically mature vessels in ischemia myocardium. |
1(0,0,0,1) | Details |
18469305 | Lloberas N, Torras J, Alperovich G, Cruzado JM, Gimenez-Bonafe P, Herrero-Fresneda I, Franquesa M, Rama I, Grinyo JM: Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats. Nephrol Dial Transplant. 2008 Oct;23(10):3111-9. Epub 2008 May 9. Animals receiving SRL showed a decrease in renal vascular endothelial growth factor (VEGF) expression. |
1(0,0,0,1) | Details |
18508041 | Huang X, Gao X, Diaz-Trelles R, Ruiz-Lozano P, Wang Z: Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180. Dev Biol. 2008 Jul 15;319(2):258-66. Epub 2008 Apr 24. Consistent with this, quantitative RT-PCR analysis indicate that the expression of genes involved in FGF, TGF, and VEGF pathways essential for coronary development are down-regulated in mutant hearts. |
1(0,0,0,1) | Details |
20106566 | Shi H, Dong L, Zhang Y, Bai Y, Zhao J, Zhang L: Protective effect of a coffee preparation (Nescafe pure (R)) against carbon tetrachloride-induced liver fibrosis in rats. Clin Nutr. 2010 Jan 26. The mRNA expression of collagen I, collagen III, bcl-2, vascular endothelial growth factor (VEGF) and transforming growth factor-beta1 (TGF-beta1) were markedly increased by CCl (4) treatment but suppressed by a coffee preparation treatment. |
1(0,0,0,1) | Details |
20150166 | Pletinck A, Consoli C, Van Landschoot M, Steppan S, Topley N, Passlick-Deetjen J, Vanholder R, Van Biesen W: Salt intake induces epithelial-to-mesenchymal transition of the peritoneal membrane in rats. Nephrol Dial Transplant. 2010 Feb 11. After 2 weeks, samples of peritoneum were taken, and TGF-beta (1), Interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) mRNA expression were quantified with qRT-PCR. |
1(0,0,0,1) | Details |
19371232 | Lubel JS, Herath CB, Tchongue J, Grace J, Jia Z, Spencer K, Casley D, Crowley P, Sievert W, Burrell LM, Angus PW: Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Clin Sci. 2009 Sep 14;117(11):375-86. In BDL rats, Ang-(1-7) improved fibrosis stage and collagen Picrosirius Red staining, and reduced content, together with decreased gene expression of collagen 1A1, alpha-SMA (smooth muscle actin), VEGF (vascular endothelial growth factor), CTGF (connective tissue growth factor), ACE and mas [the Ang-(1-7) receptor]. |
1(0,0,0,1) | Details |
18586873 | Nakashizuka H, Mitsumata M, Okisaka S, Shimada H, Kawamura A, Mori R, Yuzawa M: Clinicopathologic findings in polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4729-37. Epub 2008 Jun 27. Immunohistochemical studies were also performed to identify CD34, vascular endothelial growth factor (VEGF), CD68, alpha-smooth muscle actin (alpha-SMA) and hypoxia-inducible factor (HIF)-1alpha. |
1(0,0,0,1) | Details |
17935226 | Tugues S, Fernandez-Varo G, Munoz-Luque J, Ros J, Arroyo V, Rodes J, Friedman SL, Carmeliet P, Jimenez W, Morales-Ruiz M: Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology. 2007 Dec;46(6):1919-26. Cirrhosis progression was associated with a significant enhancement of vascular density and expression of vascular endothelial growth factor-A, angiopoietin-1, angiopoietin-2, and placental growth factor in cirrhotic livers. |
1(0,0,0,1) | Details |
18550647 | Ardura JA, Berruguete R, Ramila D, Alvarez-Arroyo MV, Esbrit P: Parathyroid hormone-related protein interacts with vascular endothelial growth factor to promote fibrogenesis in the obstructed mouse kidney. Am J Physiol Renal Physiol. 2008 Aug;295(2):F415-25. Epub 2008 Jun 11. |
9(0,0,0,9) | Details |
19781102 | Yao Q, Qu X, Yang Q, Good DA, Dai S, Kong B, Wei MQ: Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models. Mol Cancer. 2009 Sep 27;8:78. Down-regulation of CLIC4 with a generic agent or specific siRNA both significantly reduces the expression of factors related to the phenotypes and functions of myofibroblasts, such as alpha-SMA, hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF), thus reversing the myofibroblast phenotype back to fibroblasts. |
1(0,0,0,1) | Details |
19458984 | Gossl M, Herrmann J, Tang H, Versari D, Galili O, Mannheim D, Rajkumar SV, Lerman LO, Lerman A: Prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia. Basic Res Cardiol. 2009 Nov;104(6):695-706. Epub 2009 May 21. Fresh-frozen coronary tissue was used for western blotting (VEGF, TNF-alpha, LOX-1, Ikappabetaalpha and Gro-alpha) and electrophoretic mobility shift assay (EMSA, NFkappabeta). |
1(0,0,0,1) | Details |