| Name | protein C |
|---|---|
| Synonyms | A1 activator; PSAP; Protein C; CSAct; Cerebroside sulfatase activator; Cerebroside sulfate activator; Co beta glucosidase; Component C… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19551523 | Hirschfeld J, Maurer J, Jung D, Kwiecinski M, Khimji AK, Dienes HP, Fries JW, Odenthal M: Targeting myofibroblasts in model systems of fibrosis by an artificial alpha-smooth muscle-actin promoter hybrid. Mol Biotechnol. 2009 Oct;43(2):121-9. Epub 2009 Jun 24. An artificial promoter containing the -702 bp regulatory sequence of the alpha-smooth muscle actin (SMA) gene linked to the first intron enhancer sequence of the beta-actin gene and the beta-globin intron-exon junction was constructed and tested for myofibroblast-dependent gene expression using the green fluorescent protein as a reporter. |
31(0,1,1,1) | Details |
| 19963815 | Phu D, Orwin EJ: Characterizing the effects of aligned collagen fibers and derivatives on behavior of rabbit corneal fibroblasts. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4242-5. Results from this study suggest that the combined effect of an aligned scaffolding material and supplements can create a cell-matrix construct that both downregulates expression of the light scattering protein a-smooth muscle actin (alpha-sma) and supports an increased number of cell layers. |
6(0,0,1,1) | Details |
| 19054657 | Ciba P, Sturmheit TM, Petschnik AE, Kruse C, Danner S: In vitro cultures of human pancreatic stem cells: gene and protein expression of designated markers varies with passage. Ann Anat. 2009 Jan;191(1):94-103. Epub 2008 Sep 20. Both the spontaneous expression of stem cell-related mRNA and protein as well as the characteristics of spontaneous differentiation were variable. |
1(0,0,0,1) | Details |
| 18078382 | Wilson PG, Cherry JJ, Schwamberger S, Adams AM, Zhou J, Shin S, Stice SL: An SMA project report: neural cell-based assays derived from human embryonic stem cells. Stem Cells Dev. 2007 Dec;16(6):1027-41. Minigene cassettes were constructed, employing firefly luciferase or green fluorescent protein (GFP) as reporters for splicing efficiency of SMN1 and/or SMN2 under the control of the SMN1, SMN2, or cytomegalovirus (CMV) promoters. |
1(0,0,0,1) | Details |
| 19167402 | Yabanoglu S, Akkiki M, Seguelas MH, Mialet-Perez J, Parini A, Pizzinat N: Platelet derived drives the activation of rat cardiac fibroblasts by 5-HT2A receptors. J Mol Cell Cardiol. 2009 Apr;46(4):518-25. Epub 2009 Jan 9. Treatment of neonatal rat cardiac fibroblasts with platelet lysate, and the 5-HT2A receptor agonist DOI increased the expression of alpha-SMA protein, a marker of fibroblast differentiation into myofibroblasts. |
1(0,0,0,1) | Details |
| 20004561 | Katori Y, Cho BH, Song CH, Fujimiya M, Murakami G, Kawase T: Smooth-to-striated muscle transition in human esophagus: an immunohistochemical study using fetal and adult materials. Ann Anat. 2010 Feb 20;192(1):33-41. Epub 2009 Nov 10. METHODS: In horizontal sections of 10 human fetuses between 9 and 16 weeks of gestation, we identified immunoreactivity for smooth muscle actin (SMA), striated muscle myosin heavy chain (MyH), desmin, PGP9.5, S100 protein, c-kit, and CD68 in the thoracic esophagus. |
1(0,0,0,1) | Details |
| 19343312 | Rossoll W, Bassell GJ: Spinal muscular atrophy and a model for survival of motor neuron protein function in axonal ribonucleoprotein complexes. Results Probl Cell Differ. 2009;48:289-326. Spinal muscular atrophy (SMA) is a neurodegenerative disease that results from loss of function of the SMN1 gene, encoding the ubiquitously expressed survival of motor neuron (SMN) protein, a protein best known for its housekeeping role in the SMN-Gemin multiprotein complex involved in spliceosomal small nuclear ribonucleoprotein (snRNP) assembly. |
1(0,0,0,1) | Details |
| 18601974 | Mattis VB, Bowerman M, Kothary R, Lorson CL: A SMNDelta7 read-through product confers functionality to the SMNDelta7 protein. Neurosci Lett. 2008 Sep 5;442(1):54-8. Epub 2008 Jun 26. SMN2, a nearly identical copy gene, has the potential to encode the same protein as SMN1 and is retained in all SMA patients. |
1(0,0,0,1) | Details |
| 18992195 | Huang YJ, Wang ZH, Zhang JB, Liang L, Chen F, Zhao JH: [Smad7 instead of Smad6 blocks epithelial-mesenchymal transition induced by TGF-beta in human renal proximal tubule epithelial cells]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Nov;24(11):1074-8. In the Smad7-infected cells, the overexpression of Smad7 resulted in a marked decrease of alpha-SMA protein and synthesis, but a increase of E-cadherin protein, as well as the retainment of epithelial phenotypic appearance. |
1(0,0,0,1) | Details |
| 19625298 | Mattis VB, Ebert AD, Fosso MY, Chang CW, Lorson CL: Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model. Hum Mol Genet. 2009 Oct 15;18(20):3906-13. Epub 2009 Jul 21. In humans, there exists a nearly-identical copy gene known as SMN2 that encodes an identical protein as SMN1, but differs by a silent C to T transition within exon 7. |
1(0,0,0,1) | Details |
| 17962980 | Sakla MS, Lorson CL: Induction of full-length survival motor neuron by polyphenol botanical compounds. Hum Genet. 2008 Jan;122(6):635-43. Epub 2007 Oct 26. In SMA patient fibroblasts, these compounds stimulated the production of full-length SMN RNA and protein as well as the formation of SMN-containing nuclear gems. |
1(0,0,0,1) | Details |