Protein Information

Name TAK1
Synonyms NR2C2; TAK 1; TAK1; Nuclear hormone receptor TR4; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; TR2R1; TR4…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
19116914 Shi-wen X, Parapuram SK, Pala D, Chen Y, Carter DE, Eastwood M, Denton CP, Abraham DJ, Leask A: Requirement of transforming growth factor beta-activated kinase 1 for transforming growth factor beta-induced alpha-smooth muscle actin expression and extracellular matrix contraction in fibroblasts. Arthritis Rheum. 2009 Jan;60(1):234-41.


The present study was undertaken to assess whether TGFbeta-activated kinase 1 (TAK1) acts downstream of FAK/Src to mediate fibrogenic responses in fibroblasts.
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