Protein Information

Name myeloperoxidase
Synonyms 38 kDa MYELOPEROXIDASE; MPO; Myeloperoxidase; Myeloperoxidase precursor; Peroxidase (Myeloperoxidase); Myeloperoxidases; Myeloperoxidase precursors; Peroxidase (Myeloperoxidase)s

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
17660075 Dwivedi AJ, Wu R, Nguyen E, Higuchi S, Wang H, Krishnasastry K, Marini CP, Ravikumar TS, Wang P: Adrenomedullin and adrenomedullin binding protein-1 prevent acute lung injury after gut ischemia-reperfusion. J Am Coll Surg. 2007 Aug;205(2):284-93. Epub 2007 Jun 21.


Lung injury was assessed by examining lung water content, morphologic changes, and granulocyte myeloperoxidase activity.
2(0,0,0,2) Details
19408078 Berber I, Aydin C, Cevahir N, Yenisey C, Gumrukcu G, Kocbil G, Tellioglu G, Tekin K: Tempol reduces bacterial translocation after ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion. Surg Today. 2009;39(5):407-13. Epub 2009 Apr 30.


RESULTS: There was a significant increase in myeloperoxidase activity, malondialdehyde levels, and the incidence of bacterial translocation in group 2, with a decrease in glutathione levels.
1(0,0,0,1) Details
19217652 Aksu B, Umit H, Kanter M, Guzel A, Aktas C, Civelek S, Uzun H: Effects of methylene blue in reducing cholestatic oxidative stress and hepatic damage after bile-duct ligation in rats. Acta Histochem. 2010 May;112(3):259-69. Epub 2009 Feb 14.


Myeloperoxidase activity and levels of tissue hydroxyproline were determined as measures of neutrophil activation and collagen accumulation, respectively.
1(0,0,0,1) Details
19100385 Watson MJ, Ke B, Shen XD, Gao F, Busuttil RW, Kupiec-Weglinski JW, Farmer DG: Intestinal ischemia/reperfusion injury triggers activation of innate toll-like receptor 4 and adaptive chemokine programs. Transplant Proc. 2008 Dec;40(10):3339-41.


Myeloperoxidase activity increased in a time-dependent manner after IRI (2.71 0.25 at 1 hour, 2.92 0.25 at 2 hours, 4 0.16 at 4 hours, 5.1 0.25 at 24 hours vs 0.47 0.11 controls, P < .05).
1(0,0,0,1) Details
19345372 Liu KX, Li YS, Huang WQ, Li C, Liu JX, Li Y: Immediate but not delayed postconditioning during reperfusion attenuates acute lung injury induced by intestinal ischemia/reperfusion in rats: comparison with ischemic preconditioning. J Surg Res. 2009 Nov;157(1):e55-62. Epub 2008 Dec 13.


RESULTS: Histologic results showed severe damage in rat lungs in the injury group evidenced by increased lung wet/dry weight ratio and pulmonary permeability index, which was accompanied by increases in the levels of plasma TNFalpha and IL-6, the pulmonary malondialdehyde (MDA), and the pulmonary myeloperoxidase (MPO) activity and a decrease in superoxide dismutase (SOD) activity.
1(0,0,0,1) Details
20164740 Esquenazi S, He J, Li N, Bazan HE: Immunofluoresence of Rabbit Corneas After Collagen Cross-Linking Treatment With Riboflavin and Ultraviolet A. Cornea. 2010 Feb 15.


Immunohistochemistry studies of thin sections of each cornea were performed using terminal deoxynucleotyl transferase-mediated uridine triphosphate biotin nick-end labeling staining, alpha smooth muscle actin (alpha-SMA), CD-3, myeloperoxidase antibodies, and 4',6-diamidino-2-phenylindole (DAPI) counterstaining.
1(0,0,0,1) Details