Name | hnRNP Q |
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Synonyms | GRY RBP; Glycine and tyrosine rich RNA binding protein; HNRPQ; HNRPQ 1; HNRPQ1; Heterogeneous nuclear ribonucleoprotein Q; NS1 associated protein 1; NSAP 1… |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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18794368 | Chen HH, Chang JG, Lu RM, Peng TY, Tarn WY: The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (SMN2) gene. Mol Cell Biol. 2008 Nov;28(22):6929-38. Epub 2008 Sep 15. |
6(0,0,0,6) | Details |
19430205 | Singh NN, Shishimorova M, Cao LC, Gangwani L, Singh RN: A short antisense oligonucleotide masking a unique intronic motif prevents skipping of a critical exon in spinal muscular atrophy. RNA Biol. 2009 Jul;6(3):341-50. Epub 2009 Jul 14. We further demonstrate that a single low nanomolar dose of this 8-mer ASO substantially increases the levels of SMN and a host of factors including Gemin 2, Gemin 8, ZPR1, hnRNP Q and Tra2-beta1 known to be down-regulated in SMA. |
1(0,0,0,1) | Details |