| Name | thrombin |
|---|---|
| Synonyms | Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin… |
| Name | ferrous sulfate |
|---|---|
| CAS | sulfuric acid iron(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6421970 | Rosenmund A, Haeberli A, Straub PW: Blood coagulation and acute iron toxicity. J Lab Clin Med. 1984 Apr;103(4):524-33. Because the amidolytic activity of human thrombin as well as factor Xa, kallikrein, and bovine trypsin was also reversibly suppressed by ferrous sulfate as well as ferric we consider it likely that the coagulopathy occurring in iron poisoning is the consequence of a general, physiologically important phenomenon: the susceptibility of serine proteases to nontransferrin-bound Fe3+. |
84(1,1,1,4) | Details |
| 1800620 | Abou-Shady EA, Farrag HE, el-Damarawy NA, Mohamed FA, Kamel AM, Massoud AA: In vitro effects of trace elements on blood clotting and platelet function. J Egypt Public Health Assoc. 1991;66(1-2):21-48. Also, preincubation of ferrous sulphate with thrombin or with pure fibrinogen indicated that iron could produce decrease of thrombin activity as well as impairment of fibrinogen clottability. |
4(0,0,0,4) | Details |
| 12524616 | Dijkgraaf LC, Zardeneta G, Cordewener FW, Liem RS, Schmitz JP, de Bont LG, Milam SB: Crosslinking of fibrinogen and fibronectin by free radicals: a possible initial step in adhesion formation in osteoarthritis of the temporomandibular joint. J Oral Maxillofac Surg. 2003 Jan;61(1):101-11. MATERIALS AND METHODS: Physiological clot formation of fibrinogen by thrombin and free-radical-induced crosslinking of fibrinogen and of fibronectin were analyzed using spectrophotometric turbidity measurements, light-scattering techniques, polyacrylamide gel electrophoresis (PAGE), and rotary shadowing. |
1(0,0,0,1) | Details |