Protein Information

Name NF2
Synonyms ACN; BANF; Merlin; Moesin ezrin radixin like protein; NF2; Neurofibromatosis type 2; Neurofibromatosis 2; Neurofibromin 2…

Compound Information

Name 4-aminopyridine
CAS 4-pyridinamine

Reference List

PubMed Abstract RScore(About this table)
10964617 Rosenbaum C, Kamleiter M, Grafe P, Kluwe L, Mautner V, Muller HW, Hanemann CO: Enhanced proliferation and potassium conductance of Schwann cells isolated from NF2 schwannomas can be reduced by quinidine. Neurobiol Dis. 2000 Aug;7(4):483-91.

Schwann cells isolated from schwannomas of NF2 patients or multiorgan donors were treated with different concentrations of the K (+) current blockers quinidine, tetraethylammonium chloride, and 4-aminopyridine and K (+) outward currents and proliferation rates of these cells were compared.
11(0,0,1,6) Details