| 17565003 |
Tian F, Zhu CH, Zhang XW, Xie X, Xin XL, Yi YH, Lin LP, Geng MY, Ding J: Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR. Mol Pharmacol. 2007 Sep;72(3):545-52. Epub 2007 Jun 12.
Current view holds that physical interaction between alpha (v) beta (3) integrin and kinase insert domain-containing receptor (KDR) is important in regulating angiogenesis and tumor development. |
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