| Name | NPPB |
|---|---|
| Synonyms | BNP; BNP 32; Brain natriuretic peptide; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; NPPB; Natriuretic peptide precursor B; Natriuretic peptides B… |
| Name | 4-aminopyridine |
|---|---|
| CAS | 4-pyridinamine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20130208 | Han Y, Chen JD, Liu ZM, Zhou Y, Xia JH, Du X, Jin MW: Functional ion channels in mouse cardiac c-kit+ cells. Am J Physiol Cell Physiol. 2010 Feb 3. It was found that three types of ionic currents were present in mouse cardiac c-kit (+) cells, including a delayed rectifier K (+) current (IK (DR)) inhibited by 4-aminopyridine (4-AP), an inward rectifier K (+) current (I (Kir)) decreased by Ba (2+), and a volume-sensitive current (I (Cl.vol)) inhibited by 5-nitro-1-(3-phenylpropylamino) (NPPB). |
31(0,1,1,1) | Details |
| 15319384 | Yeung CH, Barfield JP, Anapolski M, Cooper TG: Volume regulation of mature and immature spermatozoa in a primate model, and possible ion channels involved. Hum Reprod. 2004 Nov;19(11):2587-93. Epub 2004 Aug 19. The chloride channel inhibitor NPPB also caused swelling of cauda spermatozoa and both quinine and NPPB decreased the efficiency of forward progression. RVD of ejaculated spermatozoa was inhibited by the K+ channel blockers quinine and 4-aminopyridine (4-AP) but not by tetraethylammonium, Ba2+ or Gd3+, or the specific potassium channel blockers charybdotoxin, margatoxin, dendrotoxin, apamin, glybenclamide or clofilium. |
2(0,0,0,2) | Details |
| 17041732 | Pi YL, Ma JH, Zhang PH, Duan JJ: -dependent channels in plasma membrane of oocytes from toad, Bufo bufo gargarizans]. Sheng Li Xue Bao. 2006 Oct 25;58(5):471-6. Potassium channel blockers (tetraethylammonium TEA, 10 mmol/L and 4-aminopyridine, 4-AP, 10 mmol/L) reduced the outward current to (23.4+/-0.72)% of the maximum. However, further addition of chloride channel blocker (5-nitro-2, 3-phenypropylamino NPPB, 30 micromol/L) could almost completely block the outward current to (2.1+/-0.08)% of the maximum. |
1(0,0,0,1) | Details |
| 12548557 | Zheng YJ, Furukawa T, Tajimi K, Inagaki N: Cl- channel blockers inhibit transition of quiescent (G0) fibroblasts into the cell cycle. J Cell Physiol. 2003 Mar;194(3):376-83. The Cl- channel blocker 5-N-2-(3-phenylpropylamino) (NPPB; 0.2 mM) inhibited entry into S phase in synchronous cells but not in asynchronous cells, while the K+ channel blocker 4-aminopyridine (4-AP) showed similar inhibitory effects in both conditions. NPPB applied only at 0-8 or 8-14 h after serum addition inhibited entry into S phase. |
1(0,0,0,1) | Details |
| 15644932 | Bagcivan I, Kaya T, Turan M, Goktas S, Demirel Y, Gursoy S: Investigation of the mechanism of -induced relaxation on the sheep sphincter of Oddi. Can J Physiol Pharmacol. 2004 Nov;82(11):935-9. -induced relaxation was not affected by N (w)-nitro methyl ester (L-NAME) (3 x 10 (-5) mol/L), methylene blue (10 (-5) mol/L), indomethacin (10 (-5) mol/L), hexamethonium (10 (-5) mol/L), glibenclamide (10 (-5) mol/L), 4-aminopyridine (10 (-3) mol/L), tetraethylammonium (3 x 10 (-4) mol/L), (10 (-6) mol/L), 5-nitro-2-(3-phenylpropylamino) (NPPB) (10 (-6) mol/L), and anthracene-9-carboxylate (9-AC) (10 (-6) mol/L), but potentiated by bupivacain (10 (-5) mol/L). |
0(0,0,0,0) | Details |