Protein Information

Name glutamine synthetase
Synonyms GLNS; GLUL; GS; Glutamate ammonia ligase; Glutamate ammonia ligase; Glutamine synthase; Glutamine synthetase; PIG43…

Compound Information

Name glyphosate
CAS

Reference List

PubMed Abstract RScore(About this table)
12723887 Miller RP, Martinson KB, Sothern RB, Durgan BR, Gunsolus JL: Circadian response of annual weeds in a natural setting to high and low application rates of four herbicides with different modes of actions. Chronobiol Int. 2003 Mar;20(2):299-324.

Four herbicides [glyphosate (GLYT), an amino acid synthesis inhibitor; glufosinate (GLUF), a glutamine synthetase inhibitor; fomesafen (FOME), a protoporphyrinogen oxidase inhibitor, and chlorimuron ethyl (CLIM), an acetolactate synthase inhibitor] were used to examine the influence of time of day of application on the control of a variety of annual broadleaf weeds in field studies conducted in Minnesota (five studies on GLYT and GLUF, three studies on FOME and CLIM).
31(0,1,1,1) Details
7761437 Guyer D, Patton D, Ward E: Evidence for cross-pathway regulation of metabolic gene expression in plants. Proc Natl Acad Sci U S A. 1995 May 23;92(11):4997-5000.


A decrease in expression of glutamine synthetase was also observed.
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15627503 Tanguy A, Boutet I, Moraga D: Molecular characterization of the glutamine synthetase gene in the Pacific oyster Crassostrea gigas: expression study in response to xenobiotic exposure and developmental stage. Biochim Biophys Acta. 2005 Jan 11;1681(2-3):116-25. Epub 2004 Nov 23.

We analyzed the expression of mRNA CgGSII using RT-PCR to follow the expression of this gene in gills and digestive gland of oysters exposed, under experimental conditions, to hypoxia and to several contaminants (hydrocarbons and two pesticide treatments, glyphosate and a mixture of atrazine, diuron and isoproturon).
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16547651 Tan S, Evans R, Singh B: Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids. 2006 Mar;30(2):195-204. Epub 2006 Mar 20.

Glyphosate affects aromatic amino acid biosynthesis by inhibiting 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS).
Glufosinate inhibits glutamine synthetase and blocks biosynthesis of glutamine.
1(0,0,0,1) Details