16569053 |
de Maria N, Becerril JM, Garcia-Plazaola JI, Hernandez A, De Felipe MR, Fernandez-Pascual M: New insights on glyphosate mode of action in nodular metabolism: Role of shikimate accumulation. J Agric Food Chem. 2006 Apr 5;54(7):2621-8.
On the basis of the role of shikimic acid and PCA in the regulation of PEPC, as potent competitive inhibitors, this additional effect provoked by glyphosate on 5-enolpyruvylshikimic-3-phosphate synthase enzyme (EPSPS; EC 2.5.1.19) inhibition would divert most PEP into the shikimate pathway, depriving energy substrates to bacteroids to maintain nitrogen fixation. |
82(1,1,1,2) |
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