Protein Information

Name PEPC
Synonyms PEPC; peptidase C; BLM hydrolase; BMH; Bleomycin hydrolase; peptidase Cs; PEPC; hydrolase H…

Compound Information

Name glyphosate
CAS

Reference List

PubMed Abstract RScore(About this table)
16569053 de Maria N, Becerril JM, Garcia-Plazaola JI, Hernandez A, De Felipe MR, Fernandez-Pascual M: New insights on glyphosate mode of action in nodular metabolism: Role of shikimate accumulation. J Agric Food Chem. 2006 Apr 5;54(7):2621-8.

On the basis of the role of shikimic acid and PCA in the regulation of PEPC, as potent competitive inhibitors, this additional effect provoked by glyphosate on 5-enolpyruvylshikimic-3-phosphate synthase enzyme (EPSPS; EC 2.5.1.19) inhibition would divert most PEP into the shikimate pathway, depriving energy substrates to bacteroids to maintain nitrogen fixation.
82(1,1,1,2) Details