| 7840792 |
Hart BW, Faiman MD: Inhibition of rat liver low Km aldehyde dehydrogenase by thiocarbamate herbicides. Biochem Pharmacol. 1995 Jan 18;49(2):157-63.
The formation of its corresponding sulfoxide, S-methyl N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO), from DETC-Me is required for low Km mitochondrial aldehyde dehydrogenase (ALDH2, EC 1.2.1.3) inhibition.
Representative herbicides studied were n-propyl, n-propylthiocarbamate ethyl ester (EPTC), molinate, vernolate, ethiolate and butylate. |
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