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Mikalsen SO, Sanner T: Increased gap junctional intercellular communication in Syrian hamster embryo cells treated with oxidative agents. Carcinogenesis. 1994 Feb;15(2):381-7.
The GJIC enhancement by H2O2 was slightly reduced by the addition of the hydroxyl radical scavenger dimethylsulphoxide or by the inhibition of catalase by amitrole.
The cAMP/protein kinase A system is the only characterized signal transduction system that is known to increase GJIC in most cell types. |
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