| Name | leptin |
|---|---|
| Synonyms | LEP; Leptin; Leptin precursor; OB; OBS; Obese protein; Obesity factor; leptin (murine obesity homolog)… |
| Name | 4-aminopyridine |
|---|---|
| CAS | 4-pyridinamine |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18097472 | Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA: Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. J Clin Invest. 2008 Jan;118(1):272-80. |
93(1,1,2,8) | Details |
| 18097479 | Diano S, Horvath TL: Anticonvulsant effects of leptin in epilepsy. . J Clin Invest. 2008 Jan;118(1):26-8. |
5(0,0,0,5) | Details |
| 16601235 | Galvez B, de Castro J, Herold D, Dubrovska G, Arribas S, Gonzalez MC, Aranguez I, Luft FC, Ramos MP, Gollasch M, Fernandez Alfonso MS: Perivascular adipose tissue and mesenteric vascular function in spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1297-302. Epub 2006 Apr 6. The Kv channel blocker 4-aminopyridine (4-AP; 2 mmol/L) increased perfusion pressure less in SHR MB than WKY and was directly correlated with the mesenteric fat amount. Plasma and mesenteric leptin were correlated with the quantity of mesenteric fat. |
1(0,0,0,1) | Details |
| 15097991 | van den Top M, Lee K, Whyment AD, Blanks AM, Spanswick D: Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus. Nat Neurosci. 2004 May;7(5):493-4. Epub 2004 Apr 18. Here we show that rat ARC neurons containing neuropeptide Y (NPY) and agouti-related protein (AgRP), which are conditional pacemakers, are activated by orexigens and inhibited by the anorexigen leptin. |
1(0,0,0,1) | Details |