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An X-ray structure of a co-crystal of a cyanamide with cathepsin K confirmed the enzyme interaction. |
113(1,2,2,3) |
Details |
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Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Tavares FX, Willard DH Jr, Wright LL: Novel and potent cyclic cyanamide-based cathepsin K inhibitors. . Bioorg Med Chem Lett. 2005 Apr 1;15(7):1815-9.
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63(0,2,2,3) |
Details |