Protein Information

Name olfactory receptor
Synonyms HSHT 2; Olfactory receptor; HSHT2; OR19 8; OR7E24P; OR7E24Q; Olfactory receptor OR19 14…

Compound Information

Name japonilure
CAS

Reference List

PubMed Abstract RScore(About this table)
12049228 Nikonov AA, Leal WS: Peripheral coding of sex pheromone and a behavioral antagonist in the Japanese beetle, Popillia japonica. J Chem Ecol. 2002 May;28(5):1075-89.

Male antennae of the Japanese beetle, Popillia japonica, possess olfactory receptor neurons (ORNs) cocompartmentalized in the same sensilla placodea, one tuned to the sex pheromone, (R)-japonilure, and the other to the detection of a behavioral antagonist, (S)-japonilure.
31(0,1,1,1) Details
9753610 Wojtasek H, Hansson BS, Leal WS: Attracted or repelled?--a matter of two neurons, one pheromone binding protein, and a chiral center. Biochem Biophys Res Commun. 1998 Sep 18;250(2):217-22.

The single neuron recording technique, on the other hand, showed that both species possess olfactory receptor neurons, colocalized in one sensillum, extremely specific to either (R)- or (S)-japonilure.
6(0,0,1,1) Details
15012384 Leal WS: Chemical ecology of phytophagous scarab beetles. Annu Rev Entomol. 1998;43:39-61.

Various other species utilize japonilure-type lactones that are produced by desaturation of fatty acids, followed by hydroxylation, chain shortening, and cyclization.
Olfactory receptor neurons (ORNs) are specifically tuned to these enantiomeric pheromones.
1(0,0,0,1) Details
18579770 Ishida Y, Leal WS: Chiral discrimination of the Japanese beetle sex pheromone and a behavioral antagonist by a pheromone-degrading enzyme. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9076-80. Epub 2008 Jun 25.

In this insect, two olfactory receptor neurons housed in antennal sensilla placodea are highly sensitive.
One neuron specifically detects the sex pheromone produced by conspecific females (R,Z)-5-(-)-(1-decenyl) oxacyclopentan-2-one [(R)-japonilure].
1(0,0,0,1) Details
12142325 Nikonov AA, Peng G, Tsurupa G, Leal WS: Unisex pheromone detectors and pheromone-binding proteins in scarab beetles. Chem Senses. 2002 Jul;27(6):495-504.

Olfaction was studied in two species of scarab beetle, Anomala octiescostata and Anomala cuprea (Coleoptera: Scarabaeidae: Rutelinae), which are temporarily isolated and use the same sex pheromone compounds, (R)-buibuilactone and (R)-japonilure.
Single sensillum recordings in A. octiescostata revealed highly sensitive olfactory receptor neurons (ORNs) (threshold <1 pg) that were tuned to the detection of the green leaf volatile compound (Z)-3-hexenyl acetate.
1(0,0,0,1) Details