Name | caspase 8 |
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Synonyms | Apoptotic cysteine protease; Apoptotic protease Mch 5; CAP 4; CAP4; CASP 8; CASP8; CASP8 protein; Caspase 8… |
Name | acrolein |
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CAS | 2-propenal |
PubMed | Abstract | RScore(About this table) | |
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17222828 | Hristova M, Heuvelmans S, van der Vliet A: mediated caspase-8 activation by acrolein. . FEBS Lett. 2007 Feb 6;581(3):361-7. Epub 2007 Jan 12. |
-dependent regulation of Fas-88(1,1,2,3) | Details |
17320762 | Tanel A, Averill-Bates DA: Activation of the death receptor pathway of apoptosis by the acrolein. Free Radic Biol Med. 2007 Mar 15;42(6):798-810. Epub 2006 Dec 14. Exposure of Chinese hamster ovary cells to acrolein caused translocation of adaptor protein Fas associated with death domain to the cytoplasmic membrane and caspase-8 activation. |
63(0,2,2,3) | Details |
15964311 | Wu SJ, Ng LT, Lin CC: activation of the proapoptotic Bcl-2 family proteins and MAPK pathway. Life Sci. 2005 Jul 8;77(8):938-51. Epub 2005 Mar 19. Treatment with 1 microM Cin resulted in an activation of caspase-8 and cleavage of Bid to its truncated form in a time-dependent pattern. |
-induced apoptosis in human PLC/PRF/5 cells through 1(0,0,0,1) | Details |
17035713 | Benesic A, Schwerdt G, Freudinger R, Mildenberger S, Groezinger F, Wollny B, Kirchhoff A, Gekle M: Chloroacetaldehyde as a sulfhydryl reagent: the role of critical thiol groups in ifosfamide nephropathy. Kidney Blood Press Res. 2006;29(5):280-93. Epub 2006 Oct 11. CAA but not acrolein inhibited the proteases caspase-3, caspase-8 and cathepsin B. |
0(0,0,0,0) | Details |