Name | aspartate aminotransferase |
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Synonyms | Aspartate Aminotransferase 1; GIG18; GOT 1; GOT1; Aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; Transaminase A; Aspartate aminotransferases… |
Name | acrolein |
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CAS | 2-propenal |
PubMed | Abstract | RScore(About this table) | |
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12365456 | Southwell JL, Yeargans GS, Kowalewski C, Seidler NW: Acrolein modifies and inhibits cytosolic aspartate aminotransferase. . J Enzyme Inhib Med Chem. 2002 Feb;17(1):19-23. |
112(1,2,2,2) | Details |
12559987 | Seidler NW, Kowalewski C: We examined the effects of on cytosolic aspartate aminotransferase (cAAT), which is an enzyme previously shown to be modified by acrolein, and |
-induced glycation affects protein topography. Arch Biochem Biophys. 2003 Feb 1;410(1):149-54.31(0,1,1,1) | Details |
17140783 | Subash Babu P, Prabuseenivasan S, Ignacimuthu S: Also restored the altered plasma enzyme (aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alkaline phosphatase and acid phosphatase) levels to near normal. |
--a potential antidiabetic agent. Phytomedicine. 2007 Jan;14(1):15-22. Epub 2006 Nov 30.1(0,0,0,1) | Details |
9169072 | Sneed RA, Grimes SD, Schultze AE, Brown AP, Ganey PE: Bacterial endotoxin enhances the hepatotoxicity of allyl Rats were pretreated with LPS (100 micrograms/kg) 2 hr before treatment with a minimally toxic dose of allyl mg/kg), and liver toxicity was assessed 18 hr later from activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in plasma and from histologic changes in liver sections. LPS treatment did not affect the activity of alcohol dehydrogenase and did not affect the rate of production of in isolated livers perfused with allyl thus, LPS does not appear to increase the metabolic bioactivation of allyl into acrolein. |
. Toxicol Appl Pharmacol. 1997 May;144(1):77-87.1(0,0,0,1) | Details |