| Name | apoprotein |
|---|---|
| Synonyms | AD2; APOE; Apo E; Apolipoprotein E; Apolipoprotein E precursor; apoprotein; Apo Es; Apolipoprotein Es… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16195596 | Arai H, Uchida K, Nakamura K: Effect of on acrolein modification of very low density lipoprotein and uptake of oxidized apolipoprotein e by hepatocytes. Biosci Biotechnol Biochem. 2005 Sep;69(9):1760-2. |
162(2,2,2,2) | Details |
| 8698873 | Palinski W, Horkko S, Miller E, Steinbrecher UP, Powell HC, Curtiss LK, Witztum JL: Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. J Clin Invest. 1996 Aug 1;98(3):800-14. Circulating IgG and IgM autoantibodies binding to -oxidized LDL, -LDL, acrolein-LDL, and LDL modified with arachidonic or oxidation products were found in apo E-deficient mice, suggesting that the respective antigens are formed in vivo. |
84(1,1,1,4) | Details |
| 17580963 | Tamamizu-Kato S, Wong JY, Jairam V, Uchida K, Raussens V, Kato H, Ruysschaert JM, Narayanaswami V: Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E. Biochemistry. 2007 Jul 17;46(28):8392-400. Epub 2007 Jun 20. |
82(1,1,1,2) | Details |
| 12392766 | Butterfield DA, Castegna A, Lauderback CM, Drake J: Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging. 2002 Sep-Oct;23(5):655-64. The epsilon-4 allele of the lipid carrier protein apolipoprotein E (APOE) allele is a risk factor for AD. Two reactive products of lipid peroxidation are the alkenals, (HNE) and 2-propenal (acrolein). |
4(0,0,0,4) | Details |
| 18988894 | Kato R, Mori C, Kitazato K, Arata S, Obama T, Mori M, Takahashi K, Aiuchi T, Takano T, Itabe H: Transient increase in plasma oxidized LDL during the progression of atherosclerosis in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):33-9. Epub 2008 Nov 6. The occurrence of lipid peroxidation products, acrolein and oxidized phosphatidylcholines, in aortic tissue were revealed by immunohistochemical staining as early as 10 weeks. |
2(0,0,0,2) | Details |
| 12010847 | Leikauf GD, Borchers MT, Prows DR, Simpson LG: Mucin apoprotein expression in COPD. . Chest. 2002 May;121(5 Suppl):166S-182S. Recent studies with acrolein and cigarette smoke have suggested that MUC5AC is inducible (accompanied by epidermal growth factor [EGF] ligand formation and the activation of EGF receptor-dependent pathways), whereas MUC5B is constitutively expressed (increasing through gland enlargement). |
1(0,0,0,1) | Details |