Protein Information

Name muscles
Synonyms COX 7a M; COX VIIa M; COX7A; COX7A1; COX7A1 protein; COX7AH; COX7AM; Cytochrome c oxidase subunit 7a H…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
15779331 Shpakov AO, Korol'kov VI, Plesneva SA, Kuznetsova LA, Pertseva MN: Effects of the C-terminal peptide of the alphaS subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles. Neurosci Behav Physiol. 2005 Feb;35(2):177-86.

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10505332 Shpakov AO, Derkach KV: [The role of sulfhydryl groups in functioning of components of adenylate cyclase signal system in smooth muscles of the mollusk Anodonta cygnea (effect of N-ethylmaleimide and p-chloromercuribenzoic acid)]. Tsitologiia. 1999;41(6):499-505.

The alkylating agent N-ethylameimide and the sulfhydryl group blocker p-chloromercuribenzoic acid (CPMA) inhibited in dose-dependent manner both basal activity of adenylyl cyclase (AC) and its activity stimulated by non-hormonal substances (forskolin, sodium fluoride, guanylilimidodiphosphate) in smooth muscles of the freshwater bivalve mollusk Anodonta cygnea.
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12723089 Jerez NC, Calkins CR, Velazco J: Prerigor injection using glycolytic inhibitors in low-quality beef muscles. J Anim Sci. 2003 Apr;81(4):997-1003.

Prerigor muscles were injected and tumbled with 10% (by weight) of one of four solutions: sodium citrate (NaC; 200 mM), sodium fluoride (NaF; 200 mM), sodium acetate (NaA; 200 mM), and calcium chloride (CaCl2; 300 mM).
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8750705 Neumann J, Kaspareit G, Kirchhefer U, Scholz H: Sodium fluoride attenuates the negative inotropic effects of muscarinic M2 and adenosine receptor agonists. Eur J Pharmacol. 1995 Dec 29;294(2-3):451-7.

Sodium fluoride increased the force of contraction in isolated guinea-pig papillary muscles concentration dependently, starting at 3 mmol/1.
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15266917 Bhatnagar M, Rao P, Bhatnagar C, Bhatnagar R: Trace element concentration in various tissues following fluoride administration to female mice. Indian J Exp Biol. 2003 Jun;41(6):652-4.

Brain, liver, kidney and muscles demonstrate significant changes in essential trace element (Cu, Zn, Mn and Fe) level in adult female mice given 30, 60 and 120 ppm sodium fluoride (NaF) in drinking water.
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9742453 Nigam R, Triggle CR, Jin JP: h1- and h2-calponins are not essential for norepinephrine- or sodium fluoride-induced contraction of rat aortic smooth muscle. J Muscle Res Cell Motil. 1998 Aug;19(6):695-703.

Despite the presence or absence of calponin, the aortic smooth muscles from the different strains of rats all develop contractions in response to the physiological agonist norepinephrine (NE) and following activation with the plasma membrane receptor-independent NaF induction.
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9223590 Gando S, Hattori Y, Akaishi Y, Nishihira J, Kanno M: Impaired contractile response to beta adrenoceptor stimulation in diabetic rat hearts: alterations in beta adrenoceptors-G protein-adenylate cyclase system and phospholamban phosphorylation. J Pharmacol Exp Ther. 1997 Jul;282(1):475-84.

Four to six weeks later, papillary muscles isolated from diabetic hearts exhibited marked reductions in the positive inotropic responses to isoproterenol, norepinephrine and epinephrine.
The abilities of isoproterenol, sodium fluoride, 5'-guanylyl imidodiphosphate and forskolin to stimulate adenylate cyclase were preserved well in membranes prepared from diabetic hearts.
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9696407 Neumann J, Scholz H: Deferoxamine blocks interactions of fluoride and carbachol in isolated mammalian cardiac preparations. Eur J Pharmacol. 1998 Jun 5;350(2-3):189-94.

In papillary muscles, carbachol reduced the positive inotropic effects of isoprenaline (10 nmol/l).
The negative inotropic effects of carbachol in isoprenaline-stimulated guinea pig papillary muscles were attenuated by additionally applied sodium fluoride (3 mmol/l).
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19886193 Burenina EA: [Activities and properties of glucose-6-phosphatase of turbellaria Phagocata sibirica and cestodes Bothriocephalus scorpii]. Zh Evol Biokhim Fiziol. 2009 Sep-Oct;45(5):472-7.

Action of various effectors (sodium fluoride, glucose, HCO3-, citrate, Cu2+, DTT, EDTA, ATP, AFP) on the enzyme activity was studied.
The obtained results and literature data demonstrate that G6Pase is present in various muscles of representatives of the animal kingdom.
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8632607 Marsh KA, Harrisss DR, Hill SJ: Desensitization of muscarinic receptor-coupled inositol phospholipid hydrolysis in human detrusor cultured smooth cells. J Urol. 1996 Apr;155(4):1439-43.


MATERIALS AND METHODS: Cell cultures were prepared from cold cup pinch biopsies of the human detrusor muscles by explant culture methods.
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