| Name | acid phosphatase |
|---|---|
| Synonyms | ACP 3; PAP; ACP3; ACPP; ACPP protein; Acid phosphatase; Acid phosphatase prostate nirs variant 1; PACP… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8948332 | Tosomba OM, Coetzer TH, Lonsdale-Eccles JD: Localisation of acid phosphatase activity on the surface of bloodstream forms of Trypanosoma congolense. Exp Parasitol. 1996 Dec;84(3):429-38. This activity appears to be from an acid phosphatase because it was enhanced at low pH values, was inhibited by the acid phosphatase inhibitor sodium fluoride, and was not inhibited by the alkaline phosphatase inhibitor tetramisole. |
4(0,0,0,4) | Details |
| 17023171 | Senna R, Simonin V, Silva-Neto MA, Fialho E: Induction of acid phosphatase activity during germination of maize (Zea mays) seeds. Plant Physiol Biochem. 2006 Jul-Sep;44(7-9):467-73. Epub 2006 Jul 5. |
3(0,0,0,3) | Details |
| 10701555 | Fetterer RH, Rhoads ML: Characterization of acid phosphatase and hydrolase in adult Haemonchus contortus. J Parasitol. 2000 Feb;86(1):1-6. The AP had a pH optimum of 4.5 and was inhibited by and sodium fluoride, but not by o-phenanthroline. |
2(0,0,0,2) | Details |
| 11414680 | Berredo-Pinho M, Peres-Sampaio CE, Chrispim PP, Belmont-Firpo R, Lemos AP, Martiny A, Vannier-Santos MA, Meyer-Fernandes JR: A Mg-dependent ecto-ATPase in Leishmania amazonensis and its possible role in acquisition and virulence. Arch Biochem Biophys. 2001 Jul 1;391(1):16-24. In the pH range from 6.8 to 8.4, in which the cells were viable, the acid phosphatase activity decreased, while the Mg (2+)-dependent ATPase activity increased. This ecto-ATPase activity was insensitive to inhibitors of other ATPase and phosphatase activities, such as oligomycin, azide, bafilomycin A (1), ouabain, vanadate, sodium fluoride, and levamizole. |
1(0,0,0,1) | Details |
| 11750998 | Jesus JB, Lopes AH, Meyer-Fernandes JR: Characterization of an ecto-ATPase of Tritrichomonas foetus. Vet Parasitol. 2002 Jan 3;103(1-2):29-42. The acid phosphatase inhibitors (vanadate and inhibited about 60-70% of the Mg (2+)-independent ecto-ATPase activity, suggesting that the ATP hydrolysis measured in the absence of any metal divalent could, at least in part, also be catalyzed by an ecto-phosphatase present in this cell. The Mg (2+)-dependent ecto-ATPase activity was insensitive to inhibitors of other ATPase and phosphatase activities, such as oligomycin, azide, bafilomycin A (1), ouabain, vanadate, sodium fluoride and levamizole. |
1(0,0,0,1) | Details |
| 10446377 | Roknabadi SM, Bose SK, Taneja V: A thiol 100 kDa, tetrameric acid phosphatase from lentil, Lens esculenta, seeds with the characteristics of protein tyrosine phosphatases. Biochim Biophys Acta. 1999 Aug 17;1433(1-2):272-80. -O- 3'-AMP and pNPP hydrolysis is potently inhibited by micromolar orthovanadate and also to nearly the same extent by sodium fluoride, and metal ions. |
2(0,0,0,2) | Details |
| 12209338 | Martinez-Grueiro MM: Acid phosphatase activity in excretion/secretion products from Heligmosomoides polygyrus adults: an indicator of the physiological status of the worms. Parasitol Res. 2002 Oct;88(10):946-9. Epub 2002 Jun 14. For both, the AP had a pH optimum of 4.0 and was inhibited by sodium fluoride, and orthovanadate. |
2(0,0,0,2) | Details |
| 11784334 | Brillard-Bourdet M, Rehault S, Juliano L, Ferrer M, Moreau T, Gauthier F: Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates. Eur J Biochem. 2002 Jan;269(1):390-5. Its N-terminal sequence and its phosphatase properties (hydrolysis of para- at low pH) were determined, and its inhibition by sodium fluoride measured. |
2(0,0,0,2) | Details |
| 12880368 | Oguro A, Kawase T, Orikasa M: NaF induces early differentiation of murine bone marrow cells along the granulocytic pathway but not the monocytic or preosteoclastic pathway in vitro. In Vitro Cell Dev Biol Anim. 2003 May-Jun;39(5-6):243-8. The stimulatory effects of sodium fluoride (NaF) on bone formation have been explained solely by its activation of osteoblasts. NaF at subtoxic concentrations (<0.5 mM) significantly up-regulated activities of several intracellular enzymes (lactate dehydrogenase, beta-glucuronidase, acid phosphatase), cellular reduction of nitroblue tetrazolium, and (NO) production; which are all accepted as general differentiation markers. |
1(0,0,0,1) | Details |
| 11686413 | Iwamura ES, Nascimento SA, Sesso A: In vitro cytochemical studies of the golgi apparatus of pancreatic acinar cells exposed to drugs that inhibit the transport of membranes and proteins. J Submicrosc Cytol Pathol. 2001 Jan-Apr;33(1-2):83-92. Lobules of rat pancreas, incubated in vitro with metabolic inhibitors (such as antimycin A, sodium fluoride, azide and were processed in order to be compared with the PM samples of the rat acinar cells. In sliced pieces of lobules, acid phosphatase (AcPase) and tiaminopirophosphatase (TPPase) activity were evaluated. |
1(0,0,0,1) | Details |
| 9474015 | Nakanishi M, Yoh K, Uchida K, Maruo S, Matsuoka A: Improved method for measuring tartrate-resistant acid phosphatase activity in serum. Clin Chem. 1998 Feb;44(2):221-5. We measured the activity of -resistant and -sensitive acid phosphatase (TrFsACP) by using 2,6-dichloro-4-acetylphenyl as substrate at pH 6.2. |
1(0,0,0,1) | Details |
| 11860933 | Xu S, Zheng G, Li M, Shu B: [Direct effects of on activities of bone morphogenetic protein] . Zhonghua Yu Fang Yi Xue Za Zhi. 2000 Jul;34(4):215-7. METHOD: A complex sample containing BMP and sodium fluoride was implanted under the abdominal skin of young male Wistar rats. The histological characteristics, and activities of alkaline phosphatase and acid phosphatase of the implanted were examined to study the effects of on biological activities of BMP. |
1(0,0,0,1) | Details |
| 17899011 | Furuhashi K: Alkaline phosphatase of Physarum polycephalum is insoluble. Arch Microbiol. 2008 Feb;189(2):151-6. Epub 2007 Sep 26. Some phosphatases including protein phosphatase and acid phosphatase have been purified from the plasmodia, but alkaline phosphatase remains to be elucidated. |
1(0,0,0,1) | Details |
| 17469495 | Dabrowska E, Balunowska M, Letko R: [Histoenzymatic study of the liver and submandibular gland of rats exposed to sodium fluoride in drinking water]. Ann Acad Med Stetin. 2006;52 Suppl 1:9-15. RESULTS: The reaction to succinate dehydrogenase in the submandibular gland and lactate dehydrogenase in hepatocytes was attenuated, while the reaction to acid phosphatase was enhanced in the liver when rats were exposed to 32.0 mg NaF/dm (3) of drinking water. |
1(0,0,0,1) | Details |
| 9232891 | Fernandes EC, Meyer-Fernandes JR, Silva-Neto MA, Vercesi AE: Trypanosoma brucei: ecto-phosphatase activity present on the surface of intact procyclic forms. Z Naturforsch C. 1997 May-Jun;52(5-6):351-8. In the membrane-enriched fractions this phosphatase activity showed to be an acid phosphatase. |
1(0,0,0,1) | Details |
| 11569111 | Liu B, Zhao Y, Chao Y, Xie Y, Wang Y: [Degradation of methamidophos by Saccharomyces rouxii WY-3] . Huan Jing Ke Xue. 2001 Jul;22(4):37-41. The strain contains a high active acid phosphatase. Inhibiting test showed that sodium fluoride could seriously inhibit the activity of acid phosphatase to release from methamidophos, wherease it make no effect on deamination of the strain WY-3 from methamidophos. |
1(0,0,0,1) | Details |
| 14629005 | Alves-Ferreira M, Dutra PM, Lopes AH, Ferreira-Pereira A, Scofano HM, Meyer-Fernandes JR: -dependent ecto-ATP diphosphohydrolase activity in Herpetomonas muscarum muscarum. Curr Microbiol. 2003 Oct;47(4):265-71. Classical inhibitors of acid phosphatases, such as orthovanadate (NaVO3), sodium fluoride (NaF), and ammonium presented no effect on this activity. |
0(0,0,0,0) | Details |
| 12209331 | dos Passos Lemos A, de Sa Pinheiro AA, de Berredo-Pinho M, Fonseca de Souza L, Motta CM, de Souza W, Meyer-Fernandes R: Ectonucleotide diphosphohydrolase activity in Crithidia deanei. Parasitol Res. 2002 Oct;88(10):905-11. Epub 2002 Jun 19. This ecto-ATPase activity was insensitive to inhibitors of other ATPase and phosphatase activities, such as oligomycin, azide, bafilomycin A (1), ouabain, vanadate, sodium fluoride and |
0(0,0,0,0) | Details |
| 10405823 | Roach HI: Association of matrix acid and alkaline phosphatases with mineralization of cartilage and endochondral bone. Histochem J. 1999 Jan;31(1):53-61. The acid phosphatase in the chondrocytes and the matrix was -resistant, but inhibited by 2 mM sodium fluoride, whereas for osteoclasts 50-100 mM sodium fluoride were required for inhibition. |
86(1,1,1,6) | Details |
| 15936965 | Dani MP, Edwards JP, Richards EH: Hydrolase activity in the venom of the pupal endoparasitic wasp, Pimpla hypochondriaca. Comp Biochem Physiol B Biochem Mol Biol. 2005 Jul;141(3):373-81. The acid phosphatase activity was inhibited in a dose dependent manner by sodium fluoride (IC (50) 4.2 x 10 (-4) M), and by cocktail inhibitor 2 (CI 2). |
85(1,1,1,5) | Details |
| 14725320 | Kneipp LF, Palmeira VF, Pinheiro AA, Alviano CS, Rozental S, Travassos LR, Meyer-Fernandes JR: Phosphatase activity on the cell wall of Fonsecaea pedrosoi. Med Mycol. 2003 Dec;41(6):469-77. The enzymatic activity was strongly inhibited by classical inhibitors of acid phosphatases such as orthovanadate (Ki = 4.23 micromol/l), (Ki = 7.53 micromol/l) and sodium fluoride (Ki = 126.78 micromol/l) in a dose-dependent manner. |
33(0,1,1,3) | Details |
| 11683365 | Dutra PM, Dias FA, Rodrigues CO, Romeiro A, Attias M, De Souza W, Lopes AH, Meyer-Fernandes JR: Platelet-activating factor modulates a secreted phosphatase activity of the trypanosomatid parasite Herpetomonas muscarum muscarum. Curr Microbiol. 2001 Oct;43(4):288-92. Classical inhibitors of acid phosphatases, such as orthovanadate (NaVO3), sodium fluoride (NaF), and ammonium promoted a decrease in this phosphatase activity. |
32(0,1,1,2) | Details |
| 12132692 | dos Passos Lemos A, Fonseca de Souza AL, de Sa Pinheiro AA, de Berredo-Pinho M, Meyer-Fernandes JR: Ecto-phosphatase activity on the cell surface of Crithidia deanei. Z Naturforsch C. 2002 May-Jun;57(5-6):500-5. Experiments using classical inhibitors of acid phosphatases, such as ZnCl2 and sodium fluoride, as well as inhibitors of phosphotyrosine phosphatase, such as orthovanadate and ammonium showed a decrease in this phosphatase activity, with different patterns of inhibition. |
31(0,1,1,1) | Details |
| 17113080 | de Sa Pinheiro AA, Amazonas JN, de Souza Barros F, De Menezes LF, Batista EJ, Silva EF, De Souza W, Meyer-Fernandes JR: Entamoeba histolytica: an ecto-phosphatase activity regulated by oxidation-reduction reactions. Exp Parasitol. 2007 Apr;115(4):352-8. Epub 2006 Nov 17. This activity presented the following biochemical characteristics: (i) it hydrolyzes p-NPP with V (max) of 8.00+/-0.22 nmol p-NP x h (-1) x 10 (-5) cells and K (m) of 2.68+/-0.25 mM; (ii) it is inhibited by acid phosphatase inhibitors, such as (K (i)=1.70+/-0.24 microM) and sodium fluoride (K (i)=0.25+/-0.02 mM); (iii) it also showed high sensitivity to phosphotyrosine phosphatase inhibitors, such as orthovanadate (K (i)=1.07+/-0.14 microM), bpV-PHEN (K (i)=0.38+/-0.02 microM) and mpV-PIC (K (i)=0.39+/-0.04 microM). |
31(0,1,1,1) | Details |
| 19442761 | Amlabu E, Nok AJ, Sallau AB: Purification and biochemical characterization of lysosomal acid phosphatases (EC 3.1.3.2) from blood stream forms, Trypanosoma brucei brucei. Parasitol Int. 2009 Sep;58(3):238-42. Epub 2009 May 13. The enzyme activities appeared to be ACP because their activities were enhanced at low pH values and inhibited by the acid phosphatase inhibitor, sodium fluoride. |
31(0,1,1,1) | Details |
| 12375165 | de Jesus JB, Podlyska TM, Hampshire A, Lopes CS, Vannier-Santos MA, Meyer-Fernandes JR: Characterization of an ecto-phosphatase activity in the human parasite Trichomonas vaginalis. Parasitol Res. 2002 Nov;88(11):991-7. Epub 2002 Jul 13. Experiments using classical inhibitors of acid phosphatases, such as ammonium and sodium fluoride, as well as inhibitors of phosphotyrosine phosphatase, such as orthovanadate, [monoperoxo (picolinato) oxovanadate (V)] (mpV-PIC) and [potassiumbisperoxo (1,10-phenanthroline) oxovanadate (V)] (bpV-PHEN), showed a decrease in this phosphatase activity, with different patterns of inhibition. |
31(0,1,1,1) | Details |
| 18944530 | Dutra PM, Rodrigues CO, Romeiro A, Grillo LA, Dias FA, Attias M, De Souza W, Lopes AH, Meyer-Fernandes JR: Characterization of ectophosphatase activities in trypanosomatid parasites of plants. Phytopathology. 2000 Sep;90(9):1032-8. Experiments using classical inhibitors of acid phosphatases such as orthovanadate (NaVO (3)) and sodium fluoride (NaF) showed a decrease in phosphatase activities. |
31(0,1,1,1) | Details |
| 18845148 | Amazonas JN, Cosentino-Gomes D, Werneck-Lacerda A, Pinheiro AA, Lanfredi-Rangel A, De Souza W, Meyer-Fernandes JR: Giardia lamblia: Characterization of ecto-phosphatase activities. Exp Parasitol. 2009 Jan;121(1):15-21. Epub 2008 Sep 26. The ecto-phosphatase activities were inhibited at high pH as well as by classical inhibitors of acid phosphatases, such as sodium fluoride and and by inorganic the final product of the reaction. |
31(0,1,1,1) | Details |
| 16442100 | Gomes SA, Fonseca de Souza AL, Silva BA, Kiffer-Moreira T, Santos-Mallet JR, Santos AL, Meyer-Fernandes JR: Trypanosoma rangeli: Differential expression of cell surface polypeptides and ecto-phosphatase activity in short and long epimastigote forms. Exp Parasitol. 2006 Apr;112(4):253-62. Epub 2006 Jan 25. Classical inhibitors of acid phosphatases, such as ammonium sodium fluoride, and zinc showed a significant decrease in these phosphatase activities, with different patterns of inhibition. |
31(0,1,1,1) | Details |
| 17419773 | Kiffer-Moreira T, de Sa Pinheiro AA, Alviano WS, Barbosa FM, Souto-Padron T, Nimrichter L, Rodrigues ML, Alviano CS, Meyer-Fernandes JR: An ectophosphatase activity in Candida parapsilosis influences the interaction of fungi with epithelial cells. FEMS Yeast Res. 2007 Jun;7(4):621-8. Epub 2007 Apr 10. The ectophosphatase activity was strongly inhibited at high pH as well as by classical inhibitors of acid phosphatases, such as orthovanadate, sodium fluoride, and inorganic the final product of the reaction. |
31(0,1,1,1) | Details |
| 17067648 | Casal AB, Oros J: Morphologic and cytochemical characteristics of blood cells of juvenile loggerhead sea turtles (Caretta caretta). Res Vet Sci. 2007 Apr;82(2):158-65. Epub 2006 Oct 25. Cytochemical stains included benzidine peroxidase, chloroacetate esterase, alpha-naphthyl esterase (with and without sodium fluoride), acid phosphatase (with and without Sudan black B, periodic acid-Schiff, and toluidine blue. |
6(0,0,1,1) | Details |