Protein Information

Name monocyte chemotactic protein 1
Synonyms CCL 2; MCAF; CCL2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
19354228 Moss RA, Zhang M, Krogh-Jespersen K: Latent nucleophilicity of dichlorocarbene. Org Lett. 2009 May 7;11(9):1947-50.

Rate constants and activation parameters are reported for additions of CCl (2) to methyl acrylate, acrylonitrile, and alpha-chloroacrylonitrile.
32(0,1,1,2) Details
15212811 Diodovich C, Bianchi MG, Bowe G, Acquati F, Taramelli R, Parent-Massin D, Gribaldo L: Response of human cord blood cells to styrene exposure: evaluation of its effects on apoptosis and gene expression by genomic technology. Toxicology. 2004 Aug 5;200(2-3):145-57.

Styrene is one of the most important monomers produced worldwide, and it finds major use in the production of polystyrene, acrylonitrile-butadiene-styrene resins and unsaturated polystyrene resins.
Furthermore, Macroarray analysis showed that styrene changed cord blood gene expression, inducing up-regulation of monocyte chemotactic protein 1 (MCP-1), and down-regulation of CC chemokine receptor type 1 (CCR-1) and SLP-76 tyrosine-phosphoprotein.
1(0,0,0,1) Details