Protein Information

Name superoxide dismutase
Synonyms IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD…

Compound Information

Name carbon disulfide
CAS carbon disulfide

Reference List

PubMed Abstract RScore(About this table)
17134958 Wronska-Nofer T, Nofer JR, Stetkiewicz J, Wierzbicka M, Bolinska H, Fobker M, Schulte H, Assmann G, von Eckardstein A: Evidence for oxidative stress at elevated plasma thiol levels in chronic exposure to carbon disulfide (CS2) and coronary heart disease. Nutr Metab Cardiovasc Dis. 2007 Sep;17(7):546-53. Epub 2006 Jul 7.

Antioxidative reserve was assessed by the determination of vitamine E, uric acid, superoxide dismutase, catalase, and glutathion peroxidase.
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18226364 Song FY, Pan GB, Zeng T, Yu LH, Xie KQ: [Effect of carbon disulfide on oxidation-antioxidation function of rat nerve tissues.]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007 Nov;25(11):641-4.

The alterations in glutathione (GSH), malondialdehyde (MDA), reactive oxygen species (ROS), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), hydrogen peroxidase (CAT) and total anti-oxidation (T-AOC) in cerebrum, spinal cord, and sciatic nerve of CS (2)-treated animals were assayed.
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8107322 Masukawa T, Nakanishi K: Protection by disulfiram and diethyldithiocarbamate against hypoxia-induced lethality in mice. Jpn J Pharmacol. 1993 Nov;63(3):279-84.

DEDC also prolonged the survival time, but the effect was less at its higher doses with decreased brain superoxide dismutase.
Of the metabolites of DEDC, the copper complex with DEDC caused a significant effect, whereas neither diethylamine nor carbon disulfide did.
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11512144 Jian L: Increased carbon disulfide-stimulated chemiluminescence in the pyrogallol-luminol system. Luminescence. 2001 Jul-Aug;16(4):281-3.

Testing was conducted with the pyrogallol-luminol system to observe the CL dynamic curve of CS2 and the inhibition by superoxide dismutase (SOD) on CL induced by CS2.
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11860926 Jian L, Chen Q: [Effect of carbon disulfide on pyrogallol- luminol auto-oxidation chemiluminescence system and superoxide anion]. Zhonghua Yu Fang Yi Xue Za Zhi. 2000 May;34(3):162-4.

METHODS: Luminescence dynamic curve of CS (2) and inhibition effect of superoxide dismutase (SOD) on intensity of chemiluminescence induced by CS (2) were studied with PA-L chemiluminescence system.
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10406149 Qingfen T, Xirang G, Weijing Y, Jianduan L, Yingli D, Zhimin H: An experimental study on damage of retina function due to toxicity of carbon disulfide and lipid peroxidation. Acta Ophthalmol Scand. 1999 Jun;77(3):298-301.

METHODS: To examine the amplitude and latency of a, b waves of the electroretinogram (ERG) and to assay the activities of total superoxide dismutases (TSOD), (EC no. 1.15.1.1), glutathione peroxidase (GSH-Px) (EC no.1.11.1.9) and malondialdehyed (MDA) in the retina of animals with experimental CS2 toxic retinopathy.
1(0,0,0,1) Details
11860947 Jiang X, Jiann L, Hu D: [A preliminary study on body level of nitric oxide in workers exposed to carbon disulfide]. Zhonghua Yu Fang Yi Xue Za Zhi. 2000 Nov;34(6):348-50.

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19070609 Sun DQ, Li AW, Li J, Li DG, Li YX, Hao-Feng, Gong MZ: Changes of lipid peroxidation in carbon disulfide-treated rat nerve tissues and serum. Chem Biol Interact. 2009 May 15;179(2-3):110-7. Epub 2008 Nov 25.

To further elucidate the mechanism and determine the biomarker of neuropathy induced by carbon disulfide (CS (2)), we performed a longitudinal observational study of reactive oxygen species (ROS), malondialdehyde (MDA), glutathione (GSH), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD) and total antioxidative capacity (T-AOC) in rat cerebral cortex, hippocampus, spinal cord and serum after 0, 2, 4, 8 and 12 weeks of CS (2) administration.
31(0,1,1,1) Details
14761423 Jian L, Lang HQ: [The inhibitory effect of Lu-Duo-Wei on carbon disulfide-induced generation of hydroxyl radicals]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2003 Oct;21(5):368-71.

OBJECTIVE: To study the scavenging effects of Lu-Duo-Wei, thiourea, superoxide dismutase, and sodium azide on carbon disulfide-induced generation of hydroxyl radicals.
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11057420 Jian L, Hu D: Antioxidative stress response in workers exposed to carbon disulfide. . Int Arch Occup Environ Health. 2000 Sep;73(7):503-6.

METHODS: Enzyme-linked immunosorbent assay (ELISA) and thiobarbituric acid test (BAT) were conducted on 67 exposed workers and 88 controlled ones in a viscose rayon factory to determine their serum cuprozinc-superoxide dismutase (CuZnSOD) and malonyldialdehyde (MDA) levels.
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