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Tan EL, Hsie AW: Mutagenicity and cytotoxicity of haloethanes as studied in the CHO/HGPRT system. Mutat Res. 1981 Oct;90(2):183-91.
When haloethanes were being tested as direct-acting agents in the Chinese hamster ovary cell/hypoxanthine-guanine phosphoribosyl transferase (CHO/HGPRT) system, ethylene dibromide (EtBr2) exhibited more cytotoxic and mutagenic activity than ethylene dichloride (EtCl2), and the mixed halogenated congener ethylene bromochloride (EtBrCl) had an intermediate effect. |
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