| Name | HEMA |
|---|---|
| Synonyms | AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII precursor; DXS1253E; F8; F8 protein; F8B… |
| Name | ethylene oxide |
|---|---|
| CAS | oxirane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19317515 | Carmella SG, Chen M, Han S, Briggs A, Jensen J, Hatsukami DK, Hecht SS: Effects of smoking cessation on eight urinary tobacco carcinogen and toxicant biomarkers. Chem Res Toxicol. 2009 Apr;22(4):734-41. The biomarkers were 1-hydroxy-2-(N-acetylcysteinyl)-3-butene (1) and 1-(N-acetylcysteinyl)-2-hydroxy-3-butene (2) [collectively called MHBMA for monohydroxybutyl and 1,2-dihydroxy-4-(N-acetylcysteinyl) butane (3) [DHBMA for dihydroxybutyl metabolites of 1,3-butadiene; 1-(N-acetylcysteinyl)-propan-3-ol (4, HPMA for 3-hydroxypropyl a metabolite of acrolein; 2-(N-acetylcysteinyl) butan-4-ol (5, HBMA for 4-hydroxybut-2-yl a metabolite of crotonaldehyde; (N-acetylcysteinyl) (6, SPMA for S-phenyl a metabolite of (N-acetylcysteinyl) (7, HEMA for 2-hydroxyethyl a metabolite of ethylene oxide; 1-hydroxypyrene (8) and its glucuronides (1-HOP), metabolites of pyrene; and 4-(methylnitrosamino)-1-(3-pyridyl)- (9) and its glucuronides (total NNAL), a biomarker of exposure to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). |
83(1,1,1,3) | Details |
| 16208632 | Arica MY, Bayramoglu G, Arica B, Yalcin E, Ito K, Yagci Y: Novel hydrogel membrane based on copoly (hydroxyethyl methacrylate/p-vinylbenzyl-poly (ethylene oxide)) for biomedical applications: properties and drug release characteristics. Macromol Biosci. 2005 Oct 20;5(10):983-92. A novel copolymer hydrogel was prepared in the membrane form using 2-hydroxyethyl methacrylate monomer (HEMA) and a macromonomer p-vinylbenzyl-poly (ethylene oxide) (V-PEO) via photoinitiated polymerization. |
37(0,1,1,7) | Details |
| 17416773 | Haufroid V, Merz B, Hofmann A, Tschopp A, Lison D, Hotz P: Exposure to ethylene oxide in hospitals: biological monitoring and influence of glutathione S-transferase and epoxide hydrolase polymorphisms. Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):796-802. This cross-sectional study aimed at examining (a) whether the urinary excretion of a metabolite of ethylene oxide, 2-hydroxyethyl (HEMA), could be used for monitoring occupational exposure and (b) whether glutathione S-transferase (GST) and epoxide hydrolase genotypes influenced biological monitoring. |
33(0,1,1,3) | Details |
| 18666198 | Schettgen T, Musiol A, Kraus T: Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Sep;22(17):2629-38. |
9(0,0,1,4) | Details |
| 20227354 | Scherer G, Urban M, Hagedorn HW, Serafin R, Feng S, Kapur S, Muhammad R, Jin Y, Sarkar M, Roethig HJ: Determination of methyl-, 2-hydroxyethyl- and 2-cyanoethylmercapturic acids as biomarkers of exposure to alkylating agents in cigarette smoke. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 24. We developed and validated a method for the simultaneous determination of methylmercapturic acid (MMA, biomarker for methylating agents such as NDMA and NNK), 2-hydroxyethylmercapturic acid (HEMA, biomarker for ethylene oxide) and 2-cyanoethylmercapturic acid (CEMA, biomarker for acrylonitrile) in human urine using deuterated internal standards of each compound. |
8(0,0,1,3) | Details |
| 15023451 | He H, Cao X, Lee LJ: Design of a novel hydrogel-based intelligent system for controlled drug release. J Control Release. 2004 Mar 24;95(3):391-402. In addition, poly (HEMA) coated with poly (ethylene oxide)/poly (propylene oxide)/poly (ethylene oxide) (PEO-PPO-PEO) surfactant was utilized to enhance mucoadhesion on the device surface. |
7(0,0,1,2) | Details |
| 19766066 | Eckert E, Drexler H, Goen T: Determination of six hydroxyalkyl mercapturic acids in human urine using hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC-ESI-MS/MS). J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 6. Additionally, the mercapturic acids of ethylene oxide (hydroxyethyl HEMA), propylene oxide (2-hydroxypropyl 2-HPMA), acrolein (3-hydroxypropyl 3-HPMA) as well as of 1,3-butadiene (3,4-dihydroxybutyl DHBMA and monohydroxy-3-butenyl MHBMA) can be determined. |
6(0,0,1,1) | Details |
| 15348420 | Prasitsilp M, Siriwittayakorn T, Molloy R, Suebsanit N, Siriwittayakorn P, Veeranondha S: Cytotoxicity study of homopolymers and copolymers of 2-hydroxyethyl methacrylate and some alkyl acrylates for potential use as temporary skin substitutes. J Mater Sci Mater Med. 2003 Jul;14(7):595-600. The cytotoxicities of both homopolymers and copolymers of 2-hydroxyethyl methacrylate (HEMA) and various alkyl acrylates (AA) were investigated using cell culture techniques. After sterilization using ethylene oxide gas, cytotoxicity tests, including both direct and indirect contact tests, were performed using cell lines of L929 and normal human dermal fibroblasts. |
2(0,0,0,2) | Details |
| 16800157 | Zeng Y, Pitt WG: A polymeric micelle system with a hydrolysable segment for drug delivery. J Biomater Sci Polym Ed. 2006;17(5):591-604. This vehicle was composed of an amphiphilic co-polymer, poly (ethylene oxide)-b-poly (N-isopropylacrylamide-co-2-hydroxyethyl methacrylate-lactate (n)). The molar ratio of NIPAAm to HEMA-lactate (n) to PEO in polymerization was optimized to produce an in vitro polymeric micelle half-life of about 48 h at 40 degrees C. 1,6-Diphenyl-1,3,5-hexatriene (DPH) was used as a fluorescent probe to study the hydrophobicity of the cores of the polymeric micelles. |
2(0,0,0,2) | Details |