| 18455923 |
Wang M, Cooley B, Gao M, Miller KD, Sledge GW, Hutchins GD, Zheng QH: Synthesis of new carbon-11 labeled naphthalene-sulfonamides for PET imaging of human CCR8. Appl Radiat Isot. 2008 Oct;66(10):1406-13. Epub 2008 Mar 20.
Carbon-11 labeled naphthalene-sulfonamides, N-(4-(N-(4-[(11) C] methoxyphenyl) sulfamoyl) naphthalene-1-yl) benzamide ([(11) C] 5a), N-(4-(N-(4-[(11) C] methoxyphenyl) sulfamoyl) naphthalene-1-yl)-2-methylbenzam ide ([(11) C] 5b), N-(4-(N-(4-[(11) C] methoxyphenyl) sulfamoyl) naphthalene-1-yl)-3-methylbenzam ide ([(11) C] 5c), N-[(11) C] methyl-N-methyl-4-(4-benzamidonaphthalene-1-sulfonamido) piperidin e-1-carboxamide ([(11) C] 9a) and N-[(11) C] methyl-N-methyl-4-(4-(2-methylbenzamido) naphthalene-1-sulfonamido ) piperidine-1-carboxamide ([(11) C] 9b), have been synthesized as new potential positron emission tomography (PET) agents for imaging of human CCR8. |
112(1,2,2,2) |
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| 17266208 |
Jenkins TJ, Guan B, Dai M, Li G, Lightburn TE, Huang S, Freeze BS, Burdi DF, Jacutin-Porte S, Bennett R, Chen W, Minor C, Ghosh S, Blackburn C, Gigstad KM, Jones M, Kolbeck R, Yin W, Smith S, Cardillo D, Ocain TD, Harriman GC: Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007 Feb 8;50(3):566-84.
The design, synthesis, and structure-activity relationship development of naphthalene-derived human CCR8 antagonists is described. |
63(0,2,2,3) |
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