| Name | Amyloid beta protein |
|---|---|
| Synonyms | A4; AD1; A4 amyloid protein; ABETA; ABPP; APP; APP751; APPI… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17510977 | Lakshmana MK, Hara H, Tabira T: Amyloid beta protein-related death-inducing protein induces G2/M arrest: Implications for neurodegeneration in Alzheimer's disease. J Neurosci Res. 2007 Aug 1;85(10):2262-71. However, etoposide, which causes genotoxic stress; tunicamycin, an ER stress inducer; and rotenone, which causes mitochondrial damage, fail to phosphorylate AB-DIP, implying that phosphorylation of AB-DIP is specific to microtubule-disruption-induced G2/M arrest. |
2(0,0,0,2) | Details |
| 15992171 | Kahle PJ, Haass C: The emerging utility of animal models of chronic neurodegenerative diseases. Expert Opin Ther Targets. 2001 Feb;5(1):125-32. Moreover, environmental risk factors such as the pesticide rotenone have been used successfully to generate rodent models of PD. A reduction of plaque burden and amelioration of cognitive decline in these animals was recently achieved by vaccination with amyloid beta-protein fibrils. |
1(0,0,0,1) | Details |