Protein Information

Name Vinculin
Synonyms MVCL; Metavinculin; VCL; Vinculin; Metavinculins; Vinculins

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
1589868 Gabai VL, Kabakov AE, Mosin AF: Association of blebbing with assembly of cytoskeletal proteins in ATP-depleted EL-4 ascites tumour cells. Tissue Cell. 1992;24(2):171-7.

After 1 hr of incubation with 2 microM rotenone (inhibitor of respiration) in glucose-free medium, when ATP level was 4% of the initial level, there were increases in triton-insoluble actin and vinculin levels (2.5-fold and 2.8-fold, respectively) and 44% of cells showed blebs; such treatment damaged cells irreversibly.
After 1 hr of incubation with 2 microM rotenone (inhibitor of respiration) in glucose-free medium, when ATP level was 4% of the initial level, there were increases in triton-insoluble actin and vinculin levels (2.5-fold and 2.8-fold, respectively) and 44% of cells showed blebs; such treatment damaged cells irreversibly.
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