Protein Information

Name NR1
Synonyms GRIN 1; NR1; GRIN1; Glutamate [NMDA] receptor subunit zeta 1; Glutamate [NMDA] receptor subunit zeta 1 precursor; N methyl D aspartate receptor subunit NR1; NMDA receptor 1; NMDA 1…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
11483661 Lu C, Chan SL, Haughey N, Lee WT, Mattson MP: Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels. J Neurochem. 2001 Aug;78(3):577-89.


The initial enhancement of NMDA-induced current is associated with increased phosphorylation of the NR1 receptor subunit, whereas the delayed suppression of current is associated with cellular ATP depletion and mitochondrial membrane depolarization.
1(0,0,0,1) Details