Protein Information

Name dynein (protein family or complex)
Synonyms Dynein; Dynein (axonemal); Dynein (cytoplasmic); Dyneins

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
2972256 Hammerstedt RH, Volonte C, Racker E: Motility, heat, and lactate production in ejaculated bovine sperm. . Arch Biochem Biophys. 1988 Oct;266(1):111-23.

We propose (a) that the bioenergetic costs of motility are divided between regulatory events and dynein-microtubule interaction (dynein ATPase), (b) that some of the membrane-related processes may be "inefficient," and (c) that quercetin may render these steps more "efficient," in a manner analogous to its action on the Na+/K+ pump of Ehrlich ascites tumor cells.
Effects of various inhibitors on motility, heat, and lactate production of ejaculated bovine sperm were determined in the presence of antimycin A and rotenone. erythro-9-[3-(2-Hydroxynonyl)] adenine (EHNA) and polyvinylpyrrolidone (PVP-360) stopped motility and reduced heat or lactate production by 30-50%.
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19137683 Samoilov VO, Bigdai EV, Rudenko IaN, Bekusova VV, Dudich BA: [Two molecular motility systems of the frog olfactory cilia] . Biofizika. 2008 Nov-Dec;53(6):993-9.

The motility of olfactory cilia of frog (Rana temporaria) was studied by vital video microscopy under an exposure to odorants: pentanol, camphor, cineole, vanillin (first group), ammonia, and hydrogen sulfide (second group) as well as inhibitors of cell respiration (rotenone and malonate).
It was shown that olfactory cilia have both a dynein-tubulin and an actin-myosin molecular motility system.
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