Protein Information

Name Interleukin 5
Synonyms B cell differentiation factor 1; B cell differentiation factor I; EDF; Eosinophil differentiation factor; IL 5; IL5; Interleukin 5; Interleukin 5 precursor…

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
17690326 Nutku-Bilir E, Hudson SA, Bochner BS: Interleukin-5 priming of human eosinophils alters siglec-8 mediated apoptosis pathways. Am J Respir Cell Mol Biol. 2008 Jan;38(1):121-4. Epub 2007 Aug 9.

Finally, both the mitochondrial electron transport inhibitor rotenone, and the ROS inhibitors diphenyleneiodonium and antimycin, completely inhibited Siglec-8-mediated apoptosis, even after IL-5 priming.
34(0,1,1,4) Details