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Volk T, Ioannidis I, Hensel M, deGroot H, Kox WJ: Endothelial damage induced by nitric oxide: synergism with reactive oxygen species. Biochem Biophys Res Commun. 1995 Aug 4;213(1):196-203.
Low doses of H2O2 producing enzymes added to low doses of SNAP (1 mM) or SNP (5 mM) substantially increased toxicity.
Non toxic doses of KCN (1 mM), antimycin A (1 microM), and rotenone (0.5 microM) in order to increase endogeneously produced reactive oxygen species increased toxic effects by 20-30% (p < 0.05). |
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