| Name | mitochondrial benzodiazepine receptor |
|---|---|
| Synonyms | BZRP; Benzodiazapine receptor peripheral; DBI; IBP; MBR; Mitochondrial benzodiazepine receptor; PBR; PBRS… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12730627 | Muscarella DE, O'Brien KA, Lemley AT, Bloom SE: Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor. Toxicol Sci. 2003 Jul;74(1):66-73. Epub 2003 May 2. We found that, although EW36 cells are refractory to apoptosis induction by antimycin A, rotenone, pyridaben, alachlor, and carbonyl m-chlorophenylhydrazone (mClCCP), they are dramatically sensitized to induction of apoptosis by low concentrations of these same agents following pre-treatment with PK11195. |
2(0,0,0,2) | Details |
| 20107899 | Veenman L, Alten J, Linnemannstons K, Shandalov Y, Zeno S, Lakomek M, Gavish M, Kugler W: Potential involvement of F (0) F (1)-ATP (synth) ase and reactive species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines : A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein. Apoptosis. 2010 Jan 28. We also previously found that the mitochondrial 18 kDa Translocator Protein (TSPO) is required for apoptosis induction by ErPC3. For this purpose, cells were treated with the ROS chelator butylated hydroxyanisole (BHA), the mitochondrial respiration chain inhibitors rotenone, antimycin A, myxothiazol, and the uncoupler CCCP. |
2(0,0,0,2) | Details |