| Name | cytochrome c1 |
|---|---|
| Synonyms | CYC 1; CYC1; Cytochrome C1; Cytochrome c 1; Cytochrome C1s; Cytochrome c 1s |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 210759 | Halestrap AP: Stimulation of the respiratory chain of rat liver mitochondria between cytochrome c1 and cytochrome c by glucagon treatment of rats. Biochem J. 1978 Jun 15;172(3):399-405. Measurement of the cytochrome spectra under uncoupled conditions in the presence of and rotenone demonstrates a crossover between cytochromes c and c (1) when control mitochondria are compared with those from glucagon-treated rats, cytochrome c being more oxidized and cytochrome c (1) more reduced in control mitochondria. |
82(1,1,1,2) | Details |
| 1664494 | Benzi G, Curti D, Pastoris O, Marzatico F, Villa RF, Dagani F: Sequential damage in mitochondrial complexes by peroxidative stress. Neurochem Res. 1991 Dec;16(12):1295-302. The following parameters are evaluated: (a) content of respiratory components, namely cytochrome b, cytochrome c1, cytochrome c; (b) specific activity of enzymes, namely citrate synthase, succinate dehydrogenase, rotenone-sensitive cytochrome c reductase, cytochrome oxidase; (c) concentration of reduced glutathione (GSH). |
6(0,0,1,1) | Details |
| 11597127 | Guidarelli A, Clementi E, De Nadai C, Bersacchi R, Cantoni O: TNFalpha enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via -dependent inhibition of complex III followed by enforced and peroxide formation. Exp Cell Res. 2001 Oct 15;270(1):56-65. The following lines of evidence suggest that the enhancing effects of TNFalpha are mediated by inhibition of complex III and by the ensuing formation of superoxides and peroxide: (a) the effects of TNFalpha were mimicked by the complex III inhibitor antimycin A; (b) the effects of TNFalpha, or antimycin A, were abolished by the complex I inhibitor rotenone, or by myxothiazol, an agent which inhibits the electron flow from the reduced to cytochrome c (1) and therefore prevents formation; (c) the effects of TNFalpha, or antimycin A, were not observed in respiration-deficient cells; and (d) the effects of TNFalpha, or antimycin A, were sensitive to catalase. |
0(0,0,0,0) | Details |
| 9396723 | Guidarelli A, Clementi E, Brambilla L, Cantoni O: Mechanism of the antimycin A-mediated enhancement of t-butylhydroperoxide-induced single-strand breakage in DNA. Biochem J. 1997 Dec 15;328 ( Pt 3):801-6. The hypothesis that these effects are selectively linked to inhibition of the electron transport from cytochrome b to cytochrome c1 is validated by the following observations: (1) two complex III inhibitors, antimycin A and 2-heptyl-4-hydroxyquinoline N-oxide, enhanced the tB-OOH-induced DNA cleavage over the same concentration range as that in which inhibition of consumption was observed; (2) the complex III inhibitor-mediated enhancement of tB-OOH-induced DNA damage was abolished by the complex I inhibitor rotenone or by omission, and (3) the enhancing effects of antimycin A were not observed in respiration-deficient cells. |
0(0,0,0,0) | Details |
| 6243963 | Malviya AN, Nicholls P, Elliott WB: Observations on the oxidoreduction of the two cytochromes b in cytochrome c-deficient mitochondria and submitochondrial particles. Biochim Biophys Acta. 1980 Jan 4;589(1):137-49. Cytochrome bT reduced in the presence of antimycin can be reoxidized by O2 if rotenone is added to an -reduced sysem or to a -reduced system. |
0(0,0,0,0) | Details |