| Name | interleukin (protein family or complex) |
|---|---|
| Synonyms | Interleukin; Interleukins; interleukin receptor; interleukin receptors |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8875956 | Corsini E, Schubert C, Marinovich M, Galli CL: Role of mitochondria in tributyltin-induced interleukin-1alpha production in murine keratinocytes. J Invest Dermatol. 1996 Nov;107(5):720-5. TBT induced a direct and concentration-related activation of NF-(kappa) B, which peaked at 2 h and was blocked by pyrrolidinedithiocarbamate, a potent NF-(kappa) B inhibitor, and rotenone, an inhibitor of the electron entry from complex I to |
2(0,0,0,2) | Details |
| 8658528 | Corsini E, Bruccoleri A, Marinovich M, Galli CL: Endogenous interleukin-1 alpha associated with skin irritation induced by tributyltin. Toxicol Appl Pharmacol. 1996 Jun;138(2):268-74. The complex-1 inhibitor rotenone also significantly inhibits IL-1alpha production. This study investigated the role of interleukin-1alpha (IL-1alpha) in the process in mice and in murine keratinocytes. |
1(0,0,0,1) | Details |
| 17102131 | Brown NM, Martin SM, Maurice N, Kuwana T, Knudson CM: Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells. J Biol Chem. 2007 Jan 26;282(4):2144-55. Epub 2006 Nov 13. Following interleukin (IL)-3 withdrawal in FL5.12 cells, Bax undergoes a conformational change that results in its mitochondria targeting, cytochrome c release, activation of caspase-9, and apoptosis. Furthermore, the "rescued" cells were resistant to rotenone, an inhibitor of mitochondrial respiration. |
1(0,0,0,1) | Details |
| 17520785 | Yi PL, Tsai CH, Lu MK, Liu HJ, Chen YC, Chang FC: Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism. Sleep. 2007 Apr 1;30(4):413-25. This study was designed to elucidate the influence of brain interleukin (IL)-1beta on sleep changes, in addition to the dopaminergic and -ergic systems, in an animal PD model. |
1(0,0,0,1) | Details |
| 10571731 | Corsini E, Asti L, Viviani B, Marinovich M, Galli CL: arsenate induces overproduction of interleukin-1alpha in murine keratinocytes: role of mitochondria. J Invest Dermatol. 1999 Nov;113(5):760-5. Prior treatment with rotenone or prolonged treatment with ethidium an inhibitor of mitochondrial DNA and RNA synthesis, to deplete cells of functional mitochondria, completely prevented arsenate-induced interleukin-1alpha production, this indicates the pivotal role of these organelles in arsenate-induced keratinocyte growth factors. |
84(1,1,1,4) | Details |