| Name | uncoupling protein 3 |
|---|---|
| Synonyms | Mitochondrial uncoupling protein 3; SLC25A9; UCP 3; UCP3; Uncoupling protein 3; Uncoupling protein 3s |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14706836 | Talbot DA, Lambert AJ, Brand MD: Production of endogenous matrix from mitochondrial complex I leads to activation of uncoupling protein 3. FEBS Lett. 2004 Jan 2;556(1-3):111-5. Both production and the GDP-sensitive conductance were suppressed by rotenone plus an antioxidant. |
3(0,0,0,3) | Details |
| 18772240 | Herlein JA, Fink BD, O'Malley Y, Sivitz WI: and respiratory coupling in mitochondria of insulin-deficient diabetic rats. Endocrinology. 2009 Jan;150(1):46-55. Epub 2008 Sep 4. Kinetic analysis of the leak showed that diabetic heart and muscle mitochondria were actually more coupled compared with control despite an approximate 2- to 4-fold increase in uncoupling protein-3 content. |
1(0,0,0,1) | Details |
| 18471434 | Lombardi A, Grasso P, Moreno M, de Lange P, Silvestri E, Lanni A, Goglia F: Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle. Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):826-33. Epub 2008 Apr 18. Mitochondrial uncoupling protein 3 (UCP (3))-mediated uncoupling has been postulated to depend on several factors, including superoxides, free fatty acids (FFAs), and fatty acid hydroperoxides and/or their derivatives. In the absence of FFAs, no differences in -leak kinetic were detected between -energized mitochondria respiring in the absence or presence of rotenone, despite a large difference in complex I production. |
1(0,0,0,1) | Details |