| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7104308 | Wolkowicz PE, Pownall HJ, McMillin-Wood JB: (I-pyrenebutyryl) and 1-pyrenebutyryl fluorescent probes for lipid metabolite studies in artificial and natural membranes. Biochemistry. 1982 Jun 8;21(12):2990-6. PBC does not inhibit and transferase or mitochondrial respiration when - or (+ rotenone) is used as the respiratory substrate. |
0(0,0,0,0) | Details |
| 1130157 | Pacanis A, Rogulski J, Ledochowski H, Angielski S: On the mechanism of action on rat kidney mitochondria. Acta Biochim Pol. 1975;22(1):1-10. and the substrates of -transferase, relieve the inhibition of metabolism by both in the respiring mitochondria and in the "anaerobic" system containing antimycin and rotenone. 4. |
31(0,1,1,1) | Details |
| 19900533 | Ishido M, Suzuki J: Inhibition by rotenone of mesencephalic neural stem-cell migration in a neurosphere assay in vitro. Toxicol In Vitro. 2010 Mar;24(2):552-7. Epub 2009 Nov 10. Exposure to rotenone inhibited cell migration, decreased proliferative cells in a dose-dependent manner, and increased the number of terminal deoxynucleotidyl transferase-mediated nick-end labeling (TUNEL)-positive cells. |
81(1,1,1,1) | Details |
| 2528539 | Levrat C, Louisot P, Morelis R: Topological investigations. J Biochem. 1989 Jul;106(1):133-8. Study of the trypsin sensitivity of the N-acetylglucosaminyl and mannosyl-transferase activities located in the outer mitochondrial membrane.. The trypsin action on mitochondrial membrane was checked by measuring the activities of marker enzymes (rotenone-insensitive cytochrome c reductase, kinase, and monoamine oxidase). |
5(0,0,0,5) | Details |
| 7391131 | Borgese N, Meldolesi J: Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. J Cell Biol. 1980 Jun;85(3):501-15. As expected, the distribution of both protein and galactosyl transferase were shifted to higher densities by this treatment. In fresh heavy and light Golgi fractions (GF3 and GF1 + 2) and in mitochondria, the specific activity of rotenone-insensitive -cytochrome c reductase was approximately 100, 60, and 30%, respectively, of the value found in microsomes. |
2(0,0,0,2) | Details |
| 8902626 | Asoh S, Mori T, Hayashi J, Ohta S: Expression of the apoptosis-mediator Fas is enhanced by dysfunctional mitochondria. J Biochem. 1996 Sep;120(3):600-7. TUNEL (terminal deoxynucleotidyl transferase mediated - nick end-labeling) and analysis of fragmented DNA indicated that the cell death of EB8 was due to apoptosis. Incubating the cells containing wild-type mtDNA with the respiratory inhibitors rotenone and antimycin A enhanced the content of mRNA of the Fas gene 2 to 4-fold and sensitized cells to the antibody. |
1(0,0,0,1) | Details |
| 18403382 | Hong HT, Nose A, Agarie S, Yoshida T: metabolism in Hoya carnosa mitochondria and its role in photosynthesis during CAM phase III. J Exp Bot. 2008;59(7):1819-27. Epub 2008 Apr 9. The mitochondria showed high malate dehydrogenase (mMDH) and amino transferase (mAST), and a significant amount of malic enzyme (mME) activities. |
1(0,0,0,1) | Details |
| 447666 | Choi YR, Clarke PR, Bieber LL: Studies on the oxidation of isobutyrylcarnitine by beef and rat liver mitochondria. J Biol Chem. 1979 Jul 10;254(13):5580-3. Mitochondria from beef liver oxidize isobutyrylcarnitine at approximately 50% the rate of in the presence of rotenone. Other studies demonstrated that less than 25% of the isobutyryl transferase activity of beef liver mitochondria and rat liver mitochondria is located on the cytosol side of the acylcoenzyme A barrier of these mitochondria. |
1(0,0,0,1) | Details |
| 18344945 | Wood JP, Lascaratos G, Bron AJ, Osborne NN: The influence of visible light exposure on cultured RGC-5 cells. Mol Vis. 2007 Feb 11;14:334-44. Treated cells were assayed for cell viability using the 3,(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) reduction assay, for DNA breakdown by terminal deoxynucleotidyl transferase (TdT)-mediated d-UTP-linked nick end labeling (TUNEL), apoptotic protein activation by immunoblotting, and the production of reactive species (ROS) with dihydroethidium. A subset of cells was treated with 100 pM rotenone as an alternative means to induce metabolic stress; this was to determine that the influence of light on compromised cells was not specific to serum-deprivation alone. |
1(0,0,0,1) | Details |
| 237982 | Broquet P, Morelis R, Louisot P: [The biosynthesis of cerebral glycoproteins: studies on mitochondrial mannosyl transferase (author's transl)] J Neurochem. 1975 May;24(5):989-95. |
1(0,0,0,1) | Details |
| 17506948 | Zhang H, Gajate C, Yu LP, Fang YX, Mollinedo F: Mitochondrial-derived ROS in edelfosine-induced apoptosis in yeasts and tumor cells. Acta Pharmacol Sin. 2007 Jun;28(6):888-94. Apoptotic yeast cells were detected using terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) assay. Rotenone, an inhibitor of the mitochondrial electron transport chain, prevented ROS generation and apoptosis in response to edelfosine in S cerevisiae. abrogated the edelfosine-induced generation of intracellular ROS and apoptosis. |
1(0,0,0,1) | Details |
| 17967937 | Kim JH, Kim JH, Yu YS, Park KH, Kang HJ, Lee HY, Kim KW: Antiangiogenic effect of deguelin on choroidal neovascularization. . J Pharmacol Exp Ther. 2008 Feb;324(2):643-7. Epub 2007 Oct 29. The toxicity of deguelin was evaluated through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium assay in human umbilical vein endothelial cells (HUVECs) as well as histological examination and terminal deoxynucleotidyl transferase nick-end labeling staining in the deguelin-injected retina. |
1(0,0,0,1) | Details |
| 171290 | Baumrucker CR, Keenan TW: Membranes of mammary gland. J Dairy Sci. 1975 Sep;58(9):1282-7. These marker enzymes include: Succinate dehydrogenase (mitochondria), cytochrome c reductase and, to a lesser extent, retenone insensitive cytochrome c reductase (endoplasmic reticulum), galactosyl transferase (Golgi apparatus), 5'-nucleotidase (plasma membranes), oxidase (microbodies), and acid phosphatase (lysosomes). Rotenone sensitive cytochrome c reductase and -stimulated triphosphatase were widely distributed among subcellular fractions and are not valid marker enzymes. |
1(0,0,0,1) | Details |
| 19885011 | Kim HJ, Song JY, Park HJ, Park HK, Yun DH, Chung JH: Protects against Rotenone-induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells. Korean J Physiol Pharmacol. 2009 Aug;13(4):281-5. Epub 2009 Aug 31. We assessed cell death and apoptosis by measuring mitogen-activated protein kinase (MAPKs) and caspase (CASPs) activities and by performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay, 4,6-diamidino-2-phenylindole (DAPI) staining, and terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) staining. |
1(0,0,0,1) | Details |
| 17367952 | Samantaray S, Knaryan VH, Guyton MK, Matzelle DD, Ray SK, Banik NL: The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience. 2007 May 11;146(2):741-55. Epub 2007 Mar 23. Dying neurons were motoneurons as identified by double immunofluorescent labeling for terminal deoxynucleotidyl transferase, recombinant-mediated nick-end labeling-positive (TUNEL (+)) cells and choline acetyltransferase (ChAT)-immunoreactivity. |
1(0,0,0,1) | Details |
| 15659217 | Li J, Spletter ML, Johnson DA, Wright LS, Svendsen CN, Johnson JA: Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells. J Neurochem. 2005 Feb;92(3):462-76. Results from ultrastructural damage and terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) staining indicated that RO-induced cytotoxicity resembled CA-induced apoptosis more than H (2) O (2)-induced necrosis. |
1(0,0,0,1) | Details |
| 18334950 | Wood JP, Lascaratos G, Bron AJ, Osborne NN: The influence of visible light exposure on cultured RGC-5 cells. Mol Vis. 2007 Feb 11;14:334-44. Treated cells were assayed for cell viability using the 3,(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) reduction assay, for DNA breakdown by terminal deoxynucleotidyl transferase (TdT)-mediated d-UTP-linked nick end labeling (TUNEL), apoptotic protein activation by immunoblotting, and the production of reactive species (ROS) with dihydroethidium. A subset of cells was treated with 100 pM rotenone as an alternative means to induce metabolic stress; this was to determine that the influence of light on compromised cells was not specific to serum-deprivation alone. |
1(0,0,0,1) | Details |
| 9059510 | Chiu KM, Schmidt MJ, Shug AL, Binkley N, Gravenstein S: Effect of on acetyl transferase activity and levels in oophorectomized rats. Biochim Biophys Acta. 1997 Feb 18;1344(3):201-9. |
1(0,0,0,1) | Details |
| 19365708 | Li R, Chen Y, Shu WX, Chen Z, Ke WJ: Involvement of SRC-3 in deguelin-induced apoptosis in Jurkat cells. Int J Hematol. 2009 Jun;89(5):628-35. Epub 2009 Apr 14. Terminal deoxynucleotide transferase-mediated nick end labeling (TUNEL) assay and transmission electron microscopy were used to detect cell apoptosis. |
1(0,0,0,1) | Details |
| 1654856 | Watkins PA, Ferrell EV Jr, Pedersen JI, Hoefler G: Peroxisomal fatty acid beta-oxidation in HepG2 cells. Arch Biochem Biophys. 1991 Sep;289(2):329-36. Peroxisomal beta-oxidation was independent of insensitive to antimycin A and rotenone, and not blocked by an inhibitor of palmitoyl transferase I. |
0(0,0,0,0) | Details |